[Betaines of quaternary salts of pyridine-2-and -4-aldoxim (author's transl)]. / Betaine quartärer Salze von Pyridin-2- und -4-aldoxim

The monobetaine derived from the AChE-ractivator bis-[4-hydroxyiminomethyl-pyridinium-(1)-methyl]-either dichloride (obidoxim; Toxogonin), was shown to be in solution an intramolecular CT-complex. Some betaines of quaternary salts of pyridine-aldoximes were isolated.

[Synthesis and Quaternation of Pyridine-aldoxim Alkylethers (author's transl)]. / Darstellung und Quaternierung von Pyridinaldoxim-alkyläthern

Using known procedures, alkylethers of pyridine-aldoxime not described as yet were prepared and transformed into pyridinium salts. The application of a solution of a,a'-di-iodo-dimethyl-ether proved especially useful in the synthesis of bisquarternary salts with formaldehyde-acetal bridge. All the new substances are ineffective in a paraoxon poisoning. On the other hand, some salts show protective action in soman intoxication.