Comparison of four different screw configurations for the fixation of Fulkerson osteotomy: a finite element analysis.

BACKGROUND: Conventionally, two 4.5 mm cortical screws inserted toward the posterior tibial cortex are usually advocated for the fixation of Fulkerson osteotomy. This finite element analysis aimed to compare the biomechanical behavior of four different screw configurations to fix the Fulkerson osteotomy. MATERIALS AND METHODS: Fulkerson osteotomy was modeled using computerized tomography (CT) data of a patient with patellofemoral instability and fixed with four different screw configurations using two 4.5 mm cortical screws in the axial plane. The configurations were as follows: (1) two screws perpendicular to the osteotomy plane, (2) two screws perpendicular to the posterior cortex of the tibia, (3) the upper screw perpendicular to the osteotomy plane, but the lower screw is perpendicular to the posterior cortex of the tibia, and (4) the reverse position of the screw configuration in the third scenario. Gap formation, sliding, displacement, frictional stress, and deformation of the components were calculated and reported. RESULTS: The osteotomy fragment moved superiorly after loading the models with 1654 N patellar tendon traction force. Since the proximal cut is sloped (bevel-cut osteotomy), the osteotomy fragment slid and rested on the upper tibial surface. Afterward, the upper surface of the osteotomy fragment acted as a fulcrum, and the distal part of the fragment began to separate from the tibia while the screws resisted the displacement. The resultant total displacement was 0.319 mm, 0.307 mm, 0.333 mm, and 0.245 mm from the first scenario to the fourth scenario, respectively. The minimum displacement was detected in the fourth scenario (upper screw perpendicular to the osteotomy plane and lower screw perpendicular to the posterior tibial cortex). Maximum frictional stress and maximum pressure between components on both surfaces were highest in the first scenario (both screws perpendicular to the osteotomy plane). CONCLUSIONS: A divergent screw configuration in which the upper screw is inserted perpendicular to the osteotomy plane and the lower screw is inserted perpendicular to the posterior tibial cortex might be a better option for the fixation of Fulkerson osteotomy. Level of evidence Level V, mechanism-based reasoning.

How to fix a tibial tubercle osteotomy with distalisation: A finite element analysis.

BACKGROUND: Antero-medialisation osteotomy combined with a distalisation procedure may require a more stable fixation as the osteotomy fragment loses both proximal and distal support. This finite element analysis aimed to compare the mechanical behaviour of different fixation techniques in tibial tubercle antero-medialisation osteotomy combined with distalisation procedure. METHODS: Tibial tubercle osteotomy combined with distalisation was modelled based on computerised tomography data, which were acquired from a patient with patellar instability requiring this procedure. Six different fixation configurations with two 3.5-mm cortical screws (1), two 4.5-mm cortical screws (2), three 3.5-mm cortical screws (3), three 4.5-mm cortical screws (4), three 3.5-mm screws with 1/3 tubular plate (5), and four 3.5-mm screws with 1/3 tubular plate (6) were created. A total of 1654 N of force was applied to the patellar tendon footprint on the tibial tubercle. Sliding, gap formation, and total deformation between the osteotomy components were analyzed. RESULTS: Maximum sliding (0.660 mm), gap formation (0.661 mm), and displacement (1.267 mm) were seen with two 3.5-mm screw fixation, followed by two 4.5-mm screws, three 3.5-mm screws, and three 4.5-mm screws, respectively, in the screw-only group. Overall, the minimum displacement was observed with the four 3.5-mm screws with 1/3 tubular plate fixation model. CONCLUSIONS: Plate fixation might be recommended for tibial tubercle antero-medialisation osteotomy combined with distalisation procedure because it might allow early active range of motion exercises and weight-bearing.

Lycopene hampers lung injury due to skeletal muscle ischemia-reperfusion in rat model.

This study investigates lycopene's preventive efficacy in skeletal muscle ischemia-reperfusion (I/R) induced lung injury. Thirty-two rats were randomly assigned to control group, lycopene group, I/R group and I/R + lycopene group. In the lycopene and I/R + lycopene groups, the rats initially received 10 mg/kg/day lycopene orally for 15 days. Then, dissection around the abdominal aorta was performed in all rats under general anesthesia. The aorta was clamped at the infrarenal level in the I/R group and I/R + lycopene group for two hours before two hours of reperfusion. The mean serum levels of malondialdehyde (53.0 ± 20.14 nmol/mL) and superoxide dismutase (1.03 ± 0.16 U/mL) were higher and lower in the I/R group than the other three groups, respectively (p < 0.001). The mean serum IMA level of I/R + lycopene group (0.42 ± 0.04 abs/u) was lower than the I/R group (0.47 ± 0.04 abs/u) (p = 0.015). The mean tissue malondialdehyde levels of I/R group (69.10 ± 11.55 nmol/mL) and I/R + lycopene group (68.36 ± 21.17 nmol/mL) were high compared to the control group (49.87 ± 6.52 nmol/mL) and lycopene group (47.82 ± 4.44 nmol/mL) (p = 0.002). The mean tissue glutathione peroxidase (p < 0.001) and superoxide dismutase (p = 0.001) levels of I/R group (121.81 ± 43.59 nmol/mL and 25.17 ± 8.69 U/mL) were low compared to the control group (236.12 ± 18.01 nmol/mL and 46.30 ± 5.17 U/mL), lycopene group (227.52 ± 16.92 nmol/mL and 45.82 ± 4.02 U/mL), and I/R + lycopene group (176.02 ± 24.27 nmol/mL and 35.20 ± 4.85 U/mL). The histopathological analyses of I/R + lycopene group indicated less significant changes than the control group. Tissue damage in the I/R + lycopene group was less prominent than the I/R group. These findings suggest oral lycopene supplementation as a promising prevention against skeletal muscle I/R caused lung injury.

Morphological Features of the Coccyx in the Turkish Population and Interrelationships Among the Parameters: A Computerized Tomography-Based Analysis.

Introduction The coccyx is well-known to be a highly variable structure considering its morphology. To our knowledge, the relationship between the coccygeal types and other morphological features has not been studied yet. In addition to the interrelations among morphological parameters, this study investigated the morphology and morphometry of coccyx more extensively in the adult Turkish population using computerized tomography images. Methods Five hundred subjects who underwent pelvic computerized tomography were included in this study. In addition to coccyx type and the counts of coccygeal vertebrae and segments, the presence of coccygeal deviation, sacrococcygeal joint (SCJ) fusion, SCJ subluxation, intercoccygeal joint (ICJ) fusion, and coccygeal spicule were evaluated. The coccygeal length, sacrococcygeal angle, and intercoccygeal angle were measured on the digital workstation. The findings were subjected to statistical analyses. Results The coccygeal vertebra count ranged between three to five, with an average of 4.04 ± 0.48. The range of coccygeal segment count was between one and five, with an average of 2.53 ± 1.02. ICJ fusion in any segment, SCJ fusion, and SCJ subluxation were identified in 397 subjects (79.4%), 343 subjects (68.6%), and 17 subjects (3.4%), respectively. The coccyx types from the most common to the least common were as follows: type 2, type 1, type 3, type 4, and type 5. Coccygeal deviation to the left side was observed in 71 subjects (14.2%), while coccygeal deviation to the right side was observed in 61 subjects (12.2%). A coccygeal spicule was identified in 73 subjects (14.6%). The subjects' mean age demonstrated no significant difference considering the ICJ fusion (p=0.271), SCJ subluxation (p=0.51), coccygeal spicule (p=0.337), features of coccygeal deviation (p=0.83), and coccyx types (p=0.11). The subjects with SCJ fusion (50.7 ± 18.3 years) were significantly older than the subjects without SCJ fusion (46.5 ± 18.5 years) (p=0.016). The differences between the coccyx types considering the rate of SCJ fusion (p=0.002), ICJ fusion (p=0.04), and spicule presence (p<0.001) as well as the coccygeal vertebra count (p<0.001) were significant. Conclusion The presence of coccygeal spicule, a risk factor for coccydynia, is reported to be 14.6% in this study group that represents the Turkish population. This study indicates an association between the coccyx types and the frequency of SCJ fusion, ICJ fusion, and spicule presence and consequently suggests the significance of the coccyx type among the morphological features to cause susceptibility to coccydynia. Due to the multiplicity of the pain generators in the coccygeal region that is established by previous reports, the comparisons of different human populations and the knowledge on the interrelations between the morphologic parameters might facilitate the comprehension of the etiology of coccydynia. The clarification of interrelationship existence among the coccygeal morphological parameters requires further investigations.

Rare isolated coracoid mid-process fracture with displacement in an adolescent: Case report.

Isolated coracoid fractures (ICFs) are rare and the management is controversial. In this article, we report a displaced ICF, treated conservatively with success. A 12-year-old male patient presented with mild pain in his right shoulder after simple fall. Physical examination was normal except mild tenderness on the coracoid process and mildly limited active shoulder motion. Plain radiographs did not demonstrate any apparent finding of pathology. Computed tomography (CT) images revealed isolated coracoid mid-process fracture with displacement. Significant symptomatic relief as well as sufficient callus formation, confirmed by follow-up CT examination, was achieved after Velpeau sling use for four weeks. After a follow-up duration of 14 months, excellent clinical and radiologic outcomes were accomplished. The result of this case supports the efficiency of conservative treatment for ICFs in adolescents, even in the presence of considerable fracture displacement. Computed tomography imaging is a valuable diagnostic tool for the assessment of ICF.

The protective effects of lycopene on ischemia/reperfusion injury in rat hind limb muscle model.

BACKGROUND: Acute ischemia/reperfusion (I/R) injury of skeletal muscle, an important mortality and morbidity cause, is associated with oxidative stress. Lycopene is a carotenoid pigment with potent antioxidant activity and is found in vegetables and fruits. This study aims to investigate the protective effects of lycopene against I/R injury in rat hind limb muscle model. METHODS: Thirty-two Wistar-albino rats were randomly allocated to control, lycopene, I/R and I/R+lycopene groups. In lycopene and I/R+lycopene groups, the rats received 10 mg/kg/day lycopene orally for 15 days before the experiment. Dissection around abdominal aorta at the infrarenal level was performed in all rats under general anesthesia. The aorta was clamped at the infrarenal level in the I/R and I/R+lycopene groups for two hours. Then, reperfusion was allowed for two hours in these groups. Samples were obtained from the hind limb muscles of rats after sacrifice for biochemical and histopathological analyses. RESULTS: Serum and tissue malondialdehyde and ischemia-modified albumin levels were significantly lower in the I/R+lycopene group compared to I/R group (p<0.001). Serum glutathione peroxidase (GSH-Px) levels were significantly lower in the I/R group compared to those in control and I/R+lycopene groups (p<0.05). Tissue GSH-Px levels were significantly lower in the I/R group compared to the Lycopene group (p=0.003). Serum superoxide dismutase (SOD) levels were significantly lower in the I/R group compared to three groups (p<0.001). Tissue SOD levels were significantly lower in the I/R group compared to those in control and Lycopene groups (p=0.005). Histopathological assessments revealed that inflammatory changes following I/R injury were significantly reduced in the I/R+lycopene group. CONCLUSION: The findings obtained in this study show lycopene's cytoprotective activity against I/R injury in rat skeletal muscle model.

Biomechanical comparison of Bunnell, modified Kessler, and Tsuge tendon repair techniques using two suture types.

OBJECTIVE: The aim of this study was to compare the biomechanical properties of modified Kessler, Bunnell and Tsuge techniques in sheep Achilles tendon tear repaired using polyester and polydioxanone sutures which are also compared. METHODS: Sixty sheep Achilles tendons were cut transversely as a substitute for rupture and repaired using modified Kessler, Bunnell and Tsuge techniques with No. 2 braided polyester and monofilament polydioxanone sutures. Specimens were loaded to failure. Four biomechanical parameters - ultimate strength (US), strength to 2 mm gap (S2G), strength to 5 mm gap (S5G) and Young's modulus (YM) - were recorded for statistical analysis. RESULTS: The Tsuge-Polyester group demonstrated the highest results regarding S2G (21.24±4.75 N) (p=.002) and S5G (38.91±7.45 N) (p=.002). According to YM, the Bunnell-Polyester group was the most superior (1929.9±512.28 kilopascal) (p=.009). In the repairs with the polydioxanone suture, Bunnell technique achieved the best purchase with regard to S2G (18.14±6.86 N) (p=.006) and S5G (35.69±13.49 N) (p=.015). The difference between the three repair techniques with the polydioxanone suture was statistically insignificant regarding US (p=.252) and YM (p=.338). Concerning the repairs with the polyester suture, the repair techniques demonstrated no statistically significant difference in terms of US (p=.195), S2G (p=.667), S5G (p=.689) and YM (p=.195). Regarding the mean S2G and S5G values, the polyester suture was significantly superior to the polydioxanone suture in modified Kessler repairs (S2G: p<.001, S5G: p=.001) and Tsuge repairs (S2G: p<.001, S5G: p=.009). The polyester suture was also significantly superior to the polydioxanone suture in the modified Kessler repairs with respect to YM (p=.003). CONCLUSION: This study supports the opinion that Tsuge technique is a promising procedure in Achilles tendon repair (ATR). For Tsuge and modified Kessler repairs, braided polyester suture use appears more advantageous compared to monofilament polydioxanone suture use in biomechanical terms.

Geometric Morphology of the Coracoacromial Ligament: A Cadaveric Study.

The coracoacromial ligament (CAL), which restrains superior displacement of humeral head, connects the acromion and coracoid process. Due to the ligament's variations and its role in shoulder pain, CAL was investigated in this study. Sixty shoulders of 34 cadavers, from persons aged 61-98 (80.95 ± 8.81) years at death time, were dissected. The lengths of lateral (LBL) and medial borders (MBL), widths of acromial (AIW) and coracoid insertions (CIW), and thicknesses of lateral (LSTAI) and medial (MSTAI) sides of acromial insertions were measured by digital caliper. The data were subjected to statistical analysis. 24 (40%) V-shaped, 12 (20%) broad-banded, 9 (15%) quadrangular, 9 (15%) Y-shaped, and 6 (10%) multiple-banded types were identified. The mean total LBL, MBL, AIW, CIW, LSTAI, and MSTAI were 34.94 ± 4.59 mm, 33.58 ± 5.31 mm, 29.82 ± 9.48 mm, 12.62 ± 3.95 mm, 1.29 ± 0.17 mm, and 0.90 ± 0.22 mm, respectively. The mean LBL (39.12 ± 4.29 mm), MBL (36.48 ± 3.9 mm), and CIW (37.01 ± 3.39 mm) were significantly greatest in quadrangular type (p<0.001). The mean AIW was slightly greatest in quadrangular type (p=0.069). The mean LSTAI was significantly greatest in multiple-banded type (1.45 ± 0.10 mm, p<0.001) whereas the mean MSTAI was significantly greatest in quadrangular type (1.23 ± 0.23 mm, p<0.001). CAL is quite variable regarding morphology, dimensions, and insertion features. Despite common knowledge, MSTAI and MBL of CAL can be greater than lateral counterparts in some types. To obtain complete release of CAL at acromion, the clearance of ligament fibers in an area with the dimensions of around 16 mm in mediolateral and 15 mm in anteroposterior direction, beginning from the lateral edge of acromial insertion, is recommended.

Radiographic analysis of the lumbar and sacral region angles in young Turkish adults.

OBJECTIVE: To determine the normal angular ranges of the lateral spinal alignments in the lumbar and sacral regions. METHODS: This cross-sectional study was conducted at the Kilis State Hospital, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey, from February to August 2017, and comprised patients aged 18-27 years who underwent standardised standing lateral lumbar radiography to eliminate hip and low back disorders. All radiographs were obtained from the hospital database as well as the demographic and contact information of each subject. Patients were invited for an interview and physical examination. Standard standing lateral radiographs of the lumbar spine were obtained from those who had no complaint of back pain and/or lower back problems. Sacro-horizontal angle, lumbosacral joint angle and sacral inclination angle were measured on the radiographic images. SPSS 22 was used to analyse data. RESULTS: Of the 150 subjects evaluated, 80(53.33%) were women and 70(46.77) were men. There was no statistically significant difference between women and men regarding lumbar lordosis angle, sacro-horizontal angle and lumbosacral angle (p>0.05). Sacral inclination angle and lower limb length in men were greater than in women (p<0.05). A positive correlation was observed between the lumbar lordosis angle, sacral inclination angle and sacro-horizontal angle values, while a negative correlation with the lumbosacral angle (p<0.05). There was no relationship observed between age, weight, height and body mass index, and sacral inclination, sacro-horizontal and lumbosacral angle values (p>0.05). Lumbar lordosis angle increased depending on the increase of the body mass index (p<0.05). CONCLUSIONS: Values identified can be considered as reference values for young healthy Turkish adults.

Morphometric Measurements of the Hip Bone in Turkish Adult Population.

OBJECTIVES: Coxal bone paticipates in the formation of the pelvic skeleton. Anatomy knowledge on coxafemoral joint as well as careful history taking and physical examination are crucial in evaluation and management of disorders involving hip joint. The aims of the present study were to perform morphometric measurements of the human coxal bones, calculation of their articular surface areas and report the range of these parameters regarding Turkish adult population. METHODS: Seventy-two dry human adult coxal bones (39 left and 33 right) from the Anatomy Departments of Erciyes University, Inonu University and Kahramanmaras Sutcu Imam University were measured using a caliper sensitive to 0.1 mm. Morphometric measurements were performed through 22 parameters determined. While 19 of these parameters were related to the distance between two points and thicknesses in various parts of the bone, the remaining three were related to the determination of articular surface areas. The articular surface areas of hip bone (facies auricularis (FA), facies lunata (FL) and facies symphsialis (FS)) were calculated with ImageJ software program. RESULTS: The average values of facies auricularis area were 1659.04 ± 470.92 mm² and 1637.32 ± 460.15 mm² on the left and right coxal bones, respectively. No statistically significant difference was determined between the left and right coxal bone measurements (p > 0.05). We found a positive and significant correlation between articular surface areas of facies auricularis (FA), facies lunata (FL) and facies symphysialis (FS) and maximum width of ilium (rFA = 0.299, rFL = 0.276, rFS = 0.375, respectively and p < 0.05), and distance between spina ilica anterior superior and the upper edge of facies symphysialis (rFA = 0.268, rFL = 0.511, rFS = 0.482, respectively and p < 0.05). CONCLUSION: The distribution and mean values of coxal bone morphometric measurements usually differ between individuals and human populations. With this regard, orthopedic surgeons should be aware of the diversity in components of coxal bone dimensions although implants and hip prosthesis components of different sizes are manufactured. Safe routes and estimated distances should be considered during surgical procedures to avoid complications.

Traction apophysitis of the fifth metatarsal base in a child: Iselin's disease.

Although Iselin's disease, apophysitis of the fifth metatarsal base, is not infrequent in clinical practice, it is accepted as a rare cause of lateral foot pain in young adolescents. Usually a simple clinical examination and radiographs are sufficient for diagnosis. We present a patient with Iselin's disease and discuss its clinical and radiographic characteristics, differential diagnosis, aetiopathogenesis and treatment.

The volar surgical approach in complex dorsal metacarpophalangeal dislocations.

OBJECTIVE: To describe the surgical treatment of complex dorsal metacarpophalangeal dislocations, emphasising the volar approach. METHODS: Seven cases of isolated, closed, complex dorsal metacarpophalangeal dislocation, treated surgically using the volar approach, were retrospectively evaluated. The median follow-up period was 91 months. RESULTS: Five of the injuries involved children. The thumb was involved in four cases and the index finger in three. The volar plate was found to impede reduction in all cases. The operated joint was immobilised in a functional brace for a median of 3 weeks. At final follow-up (median 91 months), the metacarpophalangeal range of motion, grip power, stability and sensation were normal. CONCLUSIONS: Using the volar surgical approach, the strangulated metacarpal head can be directly visualised and the volar plate, which is longitudinally split for reduction, can be repaired. Reduction should be performed within the first day from injury, and the joint should be immobilised in a functional position no more than 3 weeks.

Intramedullary K-wire fixation of pediatric forearm fractures and effects on the wrist.

This retrospective study evaluated the results of intramedullary Kirschner wire fixation in pediatric forearm fractures and the effects on the wrist. Twenty-seven patients with forearm fractures managed by limited open reduction and intramedullary K-wire fixation were included in this study. Differences in ulnar variance were examined on wrist radiographs. Average ulnar variance was -3.23 +/- 2.14 mm on the operated wrist and -2.30 +/- 2.06 mm on the contralateral wrist (P < .05).

[A comparison between locked intramedullary nailing and plate-screw fixation in the treatment of tibial diaphysis fractures]. / Tibia diafiz kiriklarinin tedavisinde intramedüller kilitli çivi ve plak-vida yöntemlerinin karsilastirilmasi.

OBJECTIVES: The results of treatment with plate-screw or locked intramedullary nailing were evaluated for tibial diaphysis fractures, with a comparison of time to union and complications. METHODS: The study included 44 patients (31 males, 13 females; mean age 38 years; range 14 to 64 years) with tibial diaphysis fractures. The fractures were on the left side in 23 patients and on the right side in 20 patients. One patient had bilateral involvement. Twenty-six fractures were treated by intramedullary nailing and 19 fractures by plate-screw fixation after a mean time of nine days and 10 days from injury, respectively. The patients were evaluated with regard to operation time, range of motion, time to union, and complications after a mean follow-up of 23 months (range 18 to 46 months). RESULTS: The mean operation time and the mean range of motion of the ankle and knee were found similar in both groups. The mean time to union was five months with intramedullary nailing, and 3.5 months with plate-screw fixation. Length discrepancy occurred in only two patients (2 and 2.5 cm) in whom intramedullary nailing was performed. One patient treated by intramedullary nailing for a type III open fracture developed osteomyelitis. Plain radiographs showed angulation in four patients and in three patients following intramedullary nailing and plate-screw fixation, respectively, all of whom had distal-third tibial fractures. CONCLUSION: Plate-screw osteosynthesis yields satisfactory results in uncomminuted fractures of the tibial diaphysis, whereas locked intramedullary nailing is more appropriate in comminuted fractures because of better preservation of periosteal circulation, and thus lower complication rates.