[Googling suicide: evaluation of websites according to the content associated with suicide]. / Internette Intihari Aramak: Internet Sitelerinin Intihar ile Iliskili Içeriklerine Göre Degerlendirilmesi.

OBJECTIVE: The Internet is increasingly being used to acquire information about personal experiences and health, but the credibility of this information is debatable. It has been reported that methods of suicide and access to suicidal means are explicitly discussed in some of the websites, with users being encouraged to attempt suicidal acts in some cases. Access to web content with pro-suicidal features is monitored in many countries. In Turkey, the frequency of people visiting these websites is unknown. Moreover, a program has not been established that targets online users. This study aims to provide information about the information that a person may come across after searching online for suicide and suicide methods in Turkish language. METHOD: After searching for particular suicidal phrases (i.e., "suicide methods," "painless suicide," "guaranteed suicide," "killing yourself" and "how can I die") in the Google search engine, three psychiatrists evaluated the results independently, according to the content. RESULTS: 42 of the 100 websites (42%) were found to have properties that are pro-suicidal, whereas 13 of them (13%) were found to have content that may be considered protective against suicidal thoughts and actions. Among the websites that were reported to be protective, none had any kind of supervision or guidance from mental health professionals. CONCLUSION: Suicidal content, as well as the possibility of content generated on the Internet, should be taken into account while planning suicide prevention programs. Further studies are needed to determine which risk factors and protective features of the Internet affect suicidal behavior among individuals.

Plasma orexin A, ghrelin, cholecystokinin, visfatin, leptin and agouti-related protein levels during 6-week olanzapine treatment in first-episode male patients with psychosis.

The objective of the study was to investigate the change of body mass index (BMI), waist circumference, lipid profile, leptin, ghrelin, orexin, visfatin, agouti-related protein, and cholecystokinin levels during 6 weeks of olanzapine treatment in newly diagnosed first-episode drug naive, young adult, nonobese male patients with psychosis. Twenty male participants who were all first-episode drug naive psychotic patients without prominent affective signs and symptoms and 22 healthy male controls of similar age were included. BMI, waist circumference, fasting glucose, and lipid profiles were measured, and Positive and Negative Syndrome Scale and Brief Psychiatric Rating Scale scores were obtained at baseline, during the second and sixth week of treatment, and the aforementioned neuropeptide levels were measured at baseline and during the sixth week of treatment. Treatment was associated with significant increases in BMI, waist circumference, serum triglyceride, and low-density lipoprotein levels. BMI levels increased more than 7% in over 75% of the patients. Leptin increased, and ghrelin and orexin decreased significantly with olanzapine treatment, whereas cholecystokinin, visfatin, and agouti-related protein levels did not change significantly. In conclusion, consistent with previous studies, we found increased BMI, leptin and lipids during olanzapine treatment. Association of neuropeptide level changes with symptom improvement might be mediated by the dopaminergic and serotonergic systems.

[The relationship between subjective sleep quality and aggression in male subjects with antisocial personality disorder]. / Antisosyal kisilik bozuklugu olan erkek bireylerde subjektif uyku kalitesinin saldirganlik ile iliskisi.

OBJECTIVE: The aim of this study was to evaluate subjective sleep quality and to determine its relationship to aggression in male subjects diagnosed with antisocial personality disorder (APD). METHODS: The study included 125 male soldiers with APD that consecutively presented to the outpatient psychiatric unit of GATA Haydarpasa Training Hospital. A control group of 125 normal volunteers with no known medical or psychiatric disorders were selected from among male military personnel. The subjects were evaluated with an assessment battery, which included the Pittsburgh Sleep Quality Index and Aggression Questionnaire, during a semi-structured interview. RESULTS: The main finding was that more of the APD patients suffered from disturbed sleep quality than did the controls. Compared to the matched controls the APD patients had lower subjective sleep quality, longer sleep latency, shorter duration of sleep, less habitual sleep efficiency, more sleep disturbances, more use of sleeping medication, and a higher level of daytime dysfunction. In the APD group, elevated levels of aggression were also significantly correlated with impaired sleep quality. CONCLUSIONS: The present study provides support for a strong link between subjective sleep quality and aggression in APD. Recognition of sleep disturbances in APD patients is also relevant to the management of APD because effective strategies to improve sleep in this patient group might also lead to vast reductions in their aggressive behaviors.