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1.
Arq Neuropsiquiatr ; 52(3): 301-8, 1994 Sep.
Article in Portuguese | MEDLINE | ID: mdl-7893201

ABSTRACT

In this controlled, prospective and partially blind study two groups of patients with temporal lobe epilepsy were evaluated, respectively with good and bad prognosis. Measurements of epileptogenesis were based on frequency of seizures, and on epiletogenic electroencephalographic abnormalities obtained from scalp electrodes over the temporal lobes. The results were analysed by non-parametric analysis of variance, comparison of groups and analysis of correlation. The results indicated the temporal lobe groups were similar to at least one of the control groups in age, sex, educational and social level, therapeutic regime, age at onset and length of history of epilepsy. The quantitative measurements showed a global difference between the group of temporal lobe with bad and good prognosis, reaching statistical significance in clinical epileptogenesis, and a trend towards greater epileptogenesis on the electroencephalogram, in the same group of patients. The results indicate the experimental usefulness of some of the original measurements used in the study, but also their problems. A review of the literature is carried out.


Subject(s)
Electroencephalography , Epilepsy, Temporal Lobe/diagnosis , Anticonvulsants , Epilepsy, Temporal Lobe/drug therapy , Female , Humans , Male , Prognosis , Prospective Studies
2.
Arq. neuropsiquiatr ; 52(3): 301-8, set. 1994. tab
Article in Portuguese | LILACS | ID: lil-141230

ABSTRACT

Neste estudo controlado, prospectivo e parcialmente cego foram avaliados dois grupos de 10 portadores de epilepsia do lobo temporal, respectivamente de bom e mau prognóstico. Foram definidas medidas de epileptogênese baseadas nas frequências de crises e na qualificaçäo de atividade epileptogênica nas derivaçöes eletrencefalográficas de lobo temporal. Os grupos de estudo foram semelhantes a no mínimo um dos grupos de controle em idade, sexo, nível educacional e social, regime terapêutico, idade de início e tempo de evoluçäo da epilepsia. Houve uma diferença global do grupo de epilepsia do lobo temporal com mau prognóstico das outras populaçöes, atingindo significado estatística em epileptogênese clínica, e uma tendência dos dados sugerindo maior epileptogênese eletrencefalográfia na mesma populaçäo. Os resultados indicam a utilidade experimental de algumas das medidas introduzidas, mas também seus problemas. Revisäo da literatura pertinente é realizada


Subject(s)
Humans , Male , Female , Electroencephalography , Epilepsy, Temporal Lobe/diagnosis , Anticonvulsants/therapeutic use , Epilepsy, Temporal Lobe/drug therapy , Prognosis , Prospective Studies
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