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Curr Opin Microbiol ; 56: 118-126, 2020 08.
Article in English | MEDLINE | ID: mdl-33147555

ABSTRACT

A myriad of microbes living together with the host constitute microbiota, which possesses very diverse functions in regulation of host physiology. Recently, it has been unequivocally demonstrated that microbiota regulates cancer initiation, progression and responses to therapy. Here we review known pro-tumorigenic and anti-tumorigenic function of microbiota and mechanisms how microbes can regulate cancer cells and immune and stromal cells within the tumor microenvironment.


Subject(s)
Microbiota , Neoplasms/microbiology , Neoplasms/therapy , Animals , Disease Progression , Humans , Immune System/immunology , Neoplasms/genetics , Neoplasms/immunology , Tumor Microenvironment
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