ABSTRACT
A retrospective cohort study was conducted to determine the 5-year survival and prognostic factors for survival for 407 oropharyngeal cancer cases registered in the 3 main hospitals in Alexandria, Egypt, from 1996-2000. Survival analysis was conducted using Kaplan-Meier curves, and multivariate Cox regression analysis. The overall 5-year survival rate was 30.8%. Multivariate analysis showed that significant prognostic factors for survival were tumour stage (hazard ratio = 2.39; 95% CI: 1.41-11.72), tumour site and patient's age. Secondary prevention of oral cancers can be conducted through examination of the oral cavity to find precancerous and early cancerous lesions and hence improve survival.
Subject(s)
Oropharyngeal Neoplasms/mortality , Urban Health/statistics & numerical data , Age Distribution , Egypt , Epidemiologic Studies , Female , Humans , Kaplan-Meier Estimate , Male , Middle Aged , Multivariate Analysis , Neoplasm Staging , Oropharyngeal Neoplasms/pathology , Oropharyngeal Neoplasms/prevention & control , Prognosis , Proportional Hazards Models , Registries , Retrospective Studies , Secondary Prevention , Sex Distribution , Survival Analysis , Survival Rate , Treatment OutcomeABSTRACT
A retrospective cohort study was conducted to determine the 5-year survival and prognostic factors for survival for 407 oropharyngeal cancer cases registered in the 3 main hospitals in Alexandria, Egypt, from 1996-2000. Survival analysis was conducted using Kaplan-Meier curves, and multivariate Cox regression analysis. The overall 5-year survival rate was 30.8%. Multivariate analysis showed that significant prognostic factors for survival were tumour stage [hazard ratio = 2.39; 95% CI: 1.41-11.72], tumour site and patient's age. Secondary prevention of oral cancers can be conducted through examination of the oral cavity to find precancerous and early cancerous lesions and hence improve survival
Subject(s)
Survival , Retrospective Studies , Cohort Studies , Prognosis , Survival Rate , Neoplasm Staging , Age Factors , Early Detection of Cancer , Oropharyngeal NeoplasmsABSTRACT
The fungal skin flora of a sample of 205 elderly persons in Alexandria, drawn by cluster sampling probability technique, was investigated. Pathogenic yeasts were isolated from 18.6% and 10.3% of skin and nails respectively. Candida albicans (16.1% and 7.3%) was prominent. A low prevalence of dermatophytes grown on agar (2.4% from skin and 2.9% from nails) was observed. In contrast, saprophytic filamentous fungi comprised 45.4 and 50.7% of skin and nails samples respectively. This study showed no statistically significant effect of sociodemographic variables (sex, marital status, crowding index, and income per capita) on the skin flora. There was no statistical significant difference between elderly diabetics and non-diabetics as regards fungal skin flora.
