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Org Lett
; 10(11): 2307-10, 2008 Jun 05.
Article
in English
| MEDLINE
| ID: mdl-18461954
ABSTRACT
Organocopper reagents smoothly react with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this novel cascade transformation, which proceeds via an SN2' substitution followed by a subsequent cycloisomerization step.