ABSTRACT
Although glandular and stromal proliferations of prostate are very common in adult men, neoplastic proliferations of prostatic stroma are distinctly uncommon. These tumors are now grouped as Prostatic Stromal Proliferations of Uncertain Malignant Potential (PSPUMP). Phyllodes tumor of the prostate is a rare neoplasm in this group with cellular, sarcomatoid stroma and benign hyperplastic glands. It is a locally expansile tumor with clinical course varying from benign to aggressive. We report a case of a 45-year-old man presented with retention of urine and abdominal lump. On laparotomy it was a huge tumor of 4 kg and was histologicaly characterized by cellular pleomorphic stroma and hyperplastic epithelium. Immunohistochemistry demonstrated prostate specific antigen in the glands. It was diagnosed as cystosarcoma phyllodes tumor of prostate. This is extremely uncommon tumor similar in histology to that of breast and it's clinical course varies with the grade. The patient was without recurrence one year after surgery.
Subject(s)
Phyllodes Tumor/pathology , Prostatic Neoplasms/pathology , Humans , Male , Middle AgedABSTRACT
OBJECTIVE: To test the sensitivity of fine needle capillary sampling (FNCS) as compared to scrape cytology in cervical carcinoma, stage III and IV, and to study the quality of material obtained by FNCS. STUDY DESIGN: Prospective. In 48 cases of cervical carcinoma, clinically stage III and IV, FNCS was done along with scrape cytology. The results were compared, considering histopathology as the gold standard. The quality of material obtained by both methods was compared using the parameters background, cellularity and cellular preservation. RESULTS: FNCS had a sensitivity of 87.5% as against 62.5% for scrape cytology. Material obtained by FNCS had a cleaner background and better cellularity and morphologic preservation. CONCLUSION: FNCS is superior to scrape cytology for the diagnosis of stage III and IV cervical carcinoma.
Subject(s)
Carcinoma/diagnosis , Carcinoma/pathology , Neoplasm Staging , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/pathology , Biopsy, Needle/standards , Female , Humans , Necrosis , Reproducibility of Results , Sensitivity and Specificity , Tissue Fixation , Vaginal Smears/standardsABSTRACT
Cystic partially differentiated nephroblastoma (CPDN) with skeletal muscle differentiation is reported for its rarity and its unique place in the spectrum from multilocular cyst to Wilms tumor. Unlike Wilms tumor CPDN does not metastasize and is cured by nephron sparing surgery.
