1.
Bioorg Med Chem Lett
; 16(15): 4085-9, 2006 Aug 01.
Article
in English
| MEDLINE
| ID: mdl-16725321
ABSTRACT
The synthesis of novel [1,2,4]oxadiazoles and their structure-activity relationship (SAR) for the inhibition of tryptase and related serine proteases is presented. Elaboration of the P'-side afforded potent, selective, and orally bioavailable tryptase inhibitors.
