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Aviakosm Ekolog Med ; 47(5): 40-4, 2013.
Article in Russian | MEDLINE | ID: mdl-24490286

ABSTRACT

Eighty outbred CD-I male and female mice (initial body mass of 31-34 g) and 40 male Wistar rats (initial body mass of 280-360 g) were randomly distributed into the experimental and control groups by sex and body mass. According to the results of experiments, consumption of rectified light-isotope water over 30 days immediately after irradiation by gamma-quanta 60Co at 5 Gy and 6.5 Gy can increase survivability rate significantly, accelerate hemopoiesis recovery and prevent body mass loss in irradiated animals. Therefore, light-isotope water can be considered as an effective agent for treatment of the bone marrow syndrome.


Subject(s)
Isotopes/pharmacology , Radiation Injuries, Experimental/radiotherapy , Water/pharmacology , Acute Disease , Animals , Dose-Response Relationship, Radiation , Female , Hematopoiesis/drug effects , Hematopoiesis/radiation effects , Male , Mice , Rats , Rats, Wistar
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