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1.
Paediatr Anaesth ; 13(8): 718-21, 2003 Oct.
Article in English | MEDLINE | ID: mdl-14535912

ABSTRACT

We describe the case of a 3-year-old boy with a subtotal amputation of the right foot who received treatment for pain via a peripheral catheter positioned at the level of the sciatic nerve (lateral approach).We administered a continuous infusion of 0.2% ropivacaine, 0.4 mg x kg(-1) x h(-1) plus clonidine 0.12 microg x kg(-1) x h(-1) for 21 days. Pain relief was complete and the patient did not require any further rescue analgesia throughout the period even during medications and surgical treatment in our intensive care unit. We discuss the safety and efficacy of the use of a peripheral continuous infusion in children compared with other techniques of analgesia.


Subject(s)
Amides/administration & dosage , Clonidine/administration & dosage , Infusion Pumps , Pain, Postoperative/prevention & control , Sciatic Nerve , Analgesics/administration & dosage , Anesthetics, Local/administration & dosage , Catheters, Indwelling , Child, Preschool , Foot/surgery , Humans , Long-Term Care/methods , Male , Nerve Block/methods , Pain Measurement , Ropivacaine
2.
Reg Anesth Pain Med ; 27(2): 157-61, 2002.
Article in English | MEDLINE | ID: mdl-11915062

ABSTRACT

BACKGROUND AND OBJECTIVES: To compare ropivacaine, levo-bupivacaine, and racemic bupivacaine for caudal blockade in children. METHODS: Using a prospective observer blinded design, 60 sevoflurane anesthetized children (1 to 7 years) undergoing minor subumbilical surgery, were randomized to receive a caudal block (1 mL/kg) with either ropivacaine 0.2%, racemic bupivacaine 0.25%, or levo-bupivacaine 0.25%. Postoperative analgesia (number of patients needing supplemental analgesia as defined by an objective pain score [OPS] score of > or = 5; time to first analgesic demand) during the first 24 postoperative hours was chosen as the primary end-point. Early postoperative motor block (3-point scale) was assessed as a secondary end-point. RESULTS: All blocks were judged to be clinically successful based on the presence of adequate intraoperative and early postoperative analgesia. An OPS score > or = 5 was found in 5/20 patients in each study group. No difference regarding the time to first analgesic demand was found between the study groups. The use of ropivacaine (P =.02), but not levo-bupivacaine (P =.18), was found to be associated with less motor block during the first postoperative hour compared with racemic bupivacaine. CONCLUSION: All 3 investigated local anesthetics were found to be clinically comparable despite the slight reduction of early postoperative motor block associated with the use of ropivacaine.


Subject(s)
Amides/therapeutic use , Anesthesia, Caudal , Anesthetics, Local/therapeutic use , Bupivacaine/therapeutic use , Pain, Postoperative/drug therapy , Child, Preschool , Female , Humans , Infant , Male , Prospective Studies , Ropivacaine , Stereoisomerism
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