ABSTRACT
The qualitative analysis of the 6 isomeric dimethylamphetamines (both methyl groups on the aromatic ring) is described. Their ultraviolet, mass, and proton magnetic resonance spectra are similar, but infrared spectra allow a positive identification to be made, and reference spectra are provided. Melting point and gas-liquid and thin layer chromatographic data are also presented.
Subject(s)
Methamphetamine/analogs & derivatives , Chromatography/methods , Isomerism , Methamphetamine/analysis , Spectrum Analysis/methodsABSTRACT
Eight 1-(1-cyanocycloalkyl) amines are identified by spectroscopic techniques. Their ultraviolet and mass spectra are similar, but proton magnetic resonance and infrared spectra are distinctly different; reference spectra and data are provided. Gas-liquid and thin layer chromatographic systems for their qualitative analysis are discussed.
Subject(s)
Amines/analysis , Phencyclidine/analogs & derivatives , Phencyclidine/chemical synthesis , Chemical Phenomena , Chemistry , Chromatography/methods , Cyclohexanes/analysis , Cyclopentanes/analysis , Nitriles/analysis , Piperidines/analysis , Spectrum Analysis/methodsABSTRACT
The qualitative analysis of the aromatic bromination products of the 6 isomeric dimethoxyamphetamines and their hydrochloride or hydrobromide salts is described. Their ultraviolet, mass, and proton magnetic resonance spectra are not sufficiently different for distinction but infrared spectra allow a positive identification to be made and reference spectra are provided for the bromination products of 2,4-, 2,5-, 2,6-, 4,5-, and 3,5-dimethoxyamphetamines. The application of gas-liquid and thin layer chromatography for the analysis of these products is discussed. The bromination of 2,3-dimethoxyamphetamine consistently gave mixtures which could not be separated satisfactorily; spectra are included for completeness of the comparison of products.
Subject(s)
Amphetamines/analysis , Bromine/analysis , DOM 2,5-Dimethoxy-4-Methylamphetamine/analogs & derivatives , Magnetic Resonance Spectroscopy , Mass Spectrometry , Spectrophotometry, Infrared , Spectrophotometry, UltravioletABSTRACT
The drugs 1-[1-(2-thienyl)cyclohexyl]piperidine, 1-[1-2-thienyl)cyclohexyl]pyrrolidine, 1-(-phenylcyclohexyl) morpholine, and 1-(1-phenyleyclohexyl) pyrrolidine are identified by spectroscopic techniques. The ultraviolet and proton magnetic resonance spectra of analogs are similar, but mass and infrared spectra are distinctly different, and reference spectra are provided. Gas-liquid ant thin layer chromatographic systems for the analysis are discussed.
