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1.
Indian J Otolaryngol Head Neck Surg ; 74(Suppl 2): 1540-1543, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36452653

ABSTRACT

Schwannomas are benign peripheral nerve sheath tumours that arise from the Schwann cells of the myelinated nerve and may occur throughout the body. Paranasal schwannomas are uncommon lesions, representing less than 4% of all head and neck schwannomas and nasal septal schwannomas are very rare. Here we report a rare case of sinonasal schwannoma in a 46-year-old male who presented with a history of progressive nasal blockage of 3 years duration. The mass was removed by endoscopic approach without any postoperative complication. The rarity of diagnosis was aided by immune histopathology (IHC) of the tissue to confirm the disease.

2.
Indian J Pathol Microbiol ; 59(3): 348-50, 2016.
Article in English | MEDLINE | ID: mdl-27510674

ABSTRACT

Extrapancreatic solid pseudopapillary neoplasms (SPNs) are rare tumors, which bear morphological, immunohistochemical, and molecular features similar to those of pancreatic counterparts. SPN occurs primarily in adolescent girls and young women. It is considered to be a malignant neoplasm with low-grade biology. Ovarian SPNs are uncommon, have benign morphology, usually limited to the ovary and local surgical excision is curative. We report an unusual case of SPN of right ovary with extraovarian spread and metastases to lymph nodes. To the best of our knowledge, this is the second documented case of extragonadal spread of ovarian SPN.


Subject(s)
Carcinoma, Papillary/diagnosis , Carcinoma, Papillary/secondary , Lymph Nodes/pathology , Neoplasm Metastasis/diagnosis , Omentum/pathology , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/secondary , Adult , Biomarkers, Tumor/analysis , CD56 Antigen/analysis , Carcinoma, Papillary/pathology , Cyclin D1/analysis , Female , Histocytochemistry , Humans , Immunohistochemistry , Microscopy , Neoplasm Metastasis/pathology , Neprilysin/analysis , Ovarian Neoplasms/pathology , Pelvis/diagnostic imaging , Tomography, X-Ray Computed , beta Catenin/analysis
3.
Indian J Pathol Microbiol ; 59(2): 206-208, 2016.
Article in English | MEDLINE | ID: mdl-27166043

ABSTRACT

Angiomyomatous hamartoma (AMH) is a rare disease with predisposition for inguinal and femoral lymph nodes. Histologically, it is characterized by replacement of lymph nodal parenchyma with irregularly distributed thick walled blood vessels, haphazardly arranged smooth muscle cells, variable amount of fat and fibrous tissue in a sclerotic lymphatic stroma. Few cases have also been reported in popliteal and sub - mandibular location. The exact pathogenesis is still not known. Although this entity is very rare, its recognition is important in discriminating it from other benign and malignant vascular lesions of lymph nodes.

4.
Indian J Pathol Microbiol ; 58(2): 220-2, 2015.
Article in English | MEDLINE | ID: mdl-25885139

ABSTRACT

Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon sarcomas that originate from a peripheral nerve or neurofibroma either spontaneously or in association with neurofibromatosis type 1. MPNSTs account for approximately 5% of all soft tissue malignancies. The tumor is commonly seen in the extremities and trunk. Most of these tumors are high-grade with the potential to recur and metastasize. Common metastatic sites include the lungs, bone, and pleura. Primary intraosseous MPNST is rare, and the diagnosis of intraosseous MPNST, especially in an unusual location is difficult because of its cellular origin, histomorphological similarities with other sarcomas, and bone is the most common site for metastasis. We report an unusual case of MPNST of the calcaneus in a young male.


Subject(s)
Bone Neoplasms/diagnosis , Bone Neoplasms/pathology , Calcaneus/pathology , Neurilemmoma/diagnosis , Neurilemmoma/pathology , Biomarkers, Tumor/analysis , Calcaneus/diagnostic imaging , Histocytochemistry , Humans , Immunohistochemistry , Keratins/analysis , Male , Microscopy , Radiography , Vimentin/analysis , Young Adult
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