ABSTRACT
Abnormal co-activation patterns of arm muscles is a substantial cause of impaired arm function after stroke. We designed a myoelectric computer interface (MCI) training paradigm to help stroke survivors reduce this abnormal coactivation. Here, we evaluated the effects of MCI training on function and arm kinematics in 32 chronic stroke survivors. We compared the effects of training duration and isometric vs. movement-based training conditions in 3 different groups. All groups reduced abnormal co-activation in targeted muscles, and showed reduced arm impairment after 6 weeks of training. They also showed improvements in arm kinematics as well as functional scores. Moreover, the gains persisted, though most were reduced, at one month after training stopped. These results suggest that MCI training holds promise to improve arm function after stroke.
