[The attitude and willingness to blood donorship among student youth of metropolis].

The shortage of blood donors is significant problem of Russian health care. The potential of involving new blood donors can be found, in particular, in activities on popularization of blood donor practices among students. The empirical study was carried out in 2022 to determine attitude of students and their willingness to take part in practices of blood donorship. The online survey of university students was implemented based on representative quota sampling of 1 135 respondents with gender, educational status and place of residence controlled. The results demonstrate complicated picture of motives and factors predetermining personal strategies and experiences of participation in blood donorship. The contradiction between positive attitude to blood donorship declared by students and passive behavioral practices was revealed. The motivation for blood donorship, mainly individual, is assessed as personal choice of student. The motivation based on altruism and desire to provide effective help is determinative. However, such obstacles of implementing blood donorship practices as insufficient information about possibilities and consequences of blood donorship, distrust of health care system, fear of blood collection procedure, lack of remuneration.

Pathogenesis, Diagnosis, and Treatment of Hemostatic Disorders in COVID-19 Patients.

The novel coronavirus infection named COVID-19 was first detected in Wuhan, China, in December 2019, and it has been responsible for significant morbidity and mortality in scores of countries. At the time this article was being written, the number of infected and deceased patients continued to grow worldwide. Most patients with severe forms of the disease suffer from pneumonia and pulmonary insufficiency; in many cases, the disease is generalized and causes multiple organ failures and a dysfunction of physiological systems. One of the most serious and prognostically ominous complications from COVID-19 is coagulopathy, in particular, decompensated hypercoagulability with the risk of developing disseminated intravascular coagulation. In most cases, local and diffuse macro- and microthromboses are present, a condition which causes multiple-organ failure and thromboembolic complications. The causes and pathogenic mechanisms of coagulopathy in COVID-19 remain largely unclear, but they are associated with systemic inflammation, including the so-called cytokine storm. Despite the relatively short period of the ongoing pandemic, laboratory signs of serious hemostatic disorders have been identified and measures for specific prevention and correction of thrombosis have been developed. This review discusses the causes of COVID-19 coagulopathies and the associated complications, as well as possible approaches to their early diagnosis, prevention, and treatment.

[Beta-adrenoblockers for the correction of arterial hypertension in postmenopausal women].

The use of beta-blockers is an important component of therapy of cardiovascular pathology (e.g. coronary heart disease, arterial hypertension) in menopausal women. Comparative data on the efficiency of lokren and carvedilol for the correction of grade 2 AH are presented.

Myocardial contractility after in vitro treatment with class III antiarrhythmic drug Nibentan.

Myocardial contractility was studied in vitro in response to treatment with class III antiarrhythmic drug Nibentan. The contractile response to Nibentan in increasing concentrations of 1.66, 2.5, and 3.5 mM was estimated on strips of animal myocardium and human right atrial auricle.