Subject(s)
Antibodies, Monoclonal/therapeutic use , Immunosuppressive Agents/therapeutic use , Kidney Transplantation/adverse effects , Lymphoproliferative Disorders/drug therapy , Postoperative Complications/drug therapy , Sirolimus/therapeutic use , Adolescent , Adult , Antibodies, Monoclonal, Murine-Derived , Humans , Male , RituximabABSTRACT
The case of a boy aged 4 yrs and 7 months, with isolated pulmonary involvement by Langerhans' cell histiocytosis is reported. The presentation of the disease was a sudden pneumothorax, with no previous signs of respiratory disease. The case was confirmed by S-100 and MT1 antibody staining, and was treated with pulse steroids and several pleural drainages, until the boy died after a large bilateral pneumothorax.
Subject(s)
Histiocytosis, Langerhans-Cell/diagnosis , Lung Diseases/diagnosis , Child, Preschool , Histiocytosis, Langerhans-Cell/complications , Histiocytosis, Langerhans-Cell/pathology , Humans , Lung/diagnostic imaging , Lung/pathology , Lung Diseases/complications , Lung Diseases/pathology , Male , Pneumothorax/etiology , RadiographyABSTRACT
Sao relatados tres casos de carcinoma verrucoso envolvendo o epitelio vulvar. Eles representam uma variante rara do carcinoma epidermoide, localmente invasiva e radiorresistente. A semelhanca dessa neoplasia com o condiloma torna dificil o diagnostico
Subject(s)
Middle Aged , Humans , Female , Vulvar Neoplasms , Carcinoma, Squamous CellABSTRACT
Sao relatados sete casos de paracoccidioidomicose com comprometimento dos orgaos genitais masculinos. Com excecao de um caso, os sintomas pulmonares precederam o envolvimento genital. O epididimo e testiculo foram os orgaos mais frequentemente atingidos. Os aspectos histopatologicos foram ressaltados
Subject(s)
Adult , Middle Aged , Humans , Male , Genital Diseases, Male , ParacoccidioidomycosisABSTRACT
A preliminary evaluation of histologic subtypes of rhabdomyosarcoma has shown that the alveolar pattern is associated with a significantly shorter survival when the patient has localized disease that has been completely excised at diagnosis. New histologic variants of undifferentiated sarcoma have been identified, but the clinical significance of these variants remains to be determined. Study of postmortem data of children placed on the Intergroup Rhabdomyosarcoma Study has shown several important clinical facts: Patients with head and neck parameningeal primary sites have a high incidence of treatment failures because the tumor extended into the adjacent central nervous system, with or without spinal fluid spread. Primary sites in the extremities and genitourinary tract are associated with an increased rate of regional lymph node spread. Systematic study of more patients is required before this association can be fully evaluated.
