[Lipids of the bone tissue in bodies of thoracic vertebrae in scoliosis in rabbits]. / Lipidy kostnoi tkani tel pozvonkov grudnogo otdela pozvonochnogo stolba krolikov pri éksperimental'nom skolioze.

The content of total lipids, triglycerides, cholesterol and phospholipids in the bone tissue of the bodies of the thoracic vertebrae was investigated in 4.5-, 7- and 12 month old rabbity. The development of scoliosis in two month old animals was induced by the one-sided blockade of the afferent links of the innervation in thoracic region at the extent of four segments (TH6-9). In: experimental scoliosis there were important alternations in the content of the total lipids comparing with the control which are observed only on the level of the primary and of the anterior compensatory curves in 12 months old animals. The content of triglycerides changed even at early stages of the development of scoliosis. A decrease of triglycerides content was observed at the level of the primary curve in rabbits of all ages with experimental scoliosis. Probably it is due to the alteration of neurotrophic processes in the bone tissue. There were similar age-related changes of triglyceride content in both groups of animals. Phospholipids have absolutely another than triglycerides dynamics of the content changes during the scoliosis development. Time-course of phospholipid changes in scoliosis differed from that of triglycerides. In older rabbits with experimental scoliosis the cholesterol content in the bone tissue of vertebral bodies was reduced by 1.5-2 times while in normal animals it remained almost unchanged. The most substantial changes in cholesterol content of the vertebral bone tissue in rabbits with the experimental scoliosis occur in early age (4.5 months) on the level of the primary curve and the posterior compensatory curve. This may be considered as one of the biochemical indicators of the progressing scoliosis.

[The vascularization characteristics of free transplants of the growth zones of the long tubular bones (experimental studies)]. / Osobennosti vaskuliarizatsii svobodnykh transplantatov rostkovykh zon dlinnykh trubchatykh kostei (éksperimental'nye issledovaniia).

The authors have studied the process of revascularization of free transplants of growth zones of the bones transplanted heterotopically from greater trochanter of the femur onto the chest. The X-ray and histological data have shown the ingrowth of the vessels into autotransplants from the side of soft tissues of the recipient bed responsible for the growth of the epiphyseal cartilage.

[Change in the makeup of the bony tissue of the spine in experimental scoliosis]. / Izmenenie sostava kostnoi tkani pozvonochnika pri éksperimental'nom skolioze.

Deveropment of experimental scoliosis in rabbits, produced by single-side rhizotomia at Th5-Th9, was accompained by accumulation of hexoses, hexoseamines and collagen in corpus vertebrae and in processus spinosus of the primary arch of curvature within all the periods of observation (23 months) as well as by an increase in content of calcium and phosphorus, occurring at the period of the scoliosis complete stabilization (10-11 months). Similar, although less distinct, alterations were found in the compensatory arch of curvature.

[Nature of the reflex excitation of the spinal motor neurons in children with isiopathic scoliosis]. / Kharakter reflektornoi vozbudimosti spinal'nykh motoneironov u detei s idiopathicheskim skoliozom.

In 32 girls from 12-14 years with expressed idiopathic scoliosis (III-IV stage) the authors studied H-reflexes, evoked from the soleus muscles. In 16 patients they established an expressed asymmetry in the expressivity of H-reflexes from the right and left sides. This asymmetry was found in a localization of the primary arch of spinal distortion in the sacral part. In a localization of the primary arch in the thoracal part, the asymmetry in the reflectory excitation of sacral motoneurons is not expressed. It is being assumed that changes in the motoneuron apparatus of the spinal cord are the reason of the appearance of a scoliotic deformation of the spine.

[Bioelectric activity of paravertebral muscles in experimental scoliosis]. / Bioélektricheskaia aktivnost' paravertebral'nykh myshts pri ékaperimental'nom skolioze

The paper is concerned with a study of the bioelectrical activity of the paravertebral muscles in 2 groups of rabbits with differently expressed degrees of experimental scoliosis and in a control group of intact animals. The results demonstrated an asymmetry in the tonic bioelectric activity in the paravertebral muscles in scoliosis, unlike the reactions of the control group of animals. The character of asymmetry depends upon the degree of deformation: in cases of moderately expressed scoliosis there is a prevalence of the tonic bioelectric activity on the level of the basic arc of distortion on the side of the concavity; in severely expressed scoliosis the tonic bioelectrical activity of the paravertebral muscles on the concave side appears to be less than on the convex side. An asymmetry of the tonic activity takes place on the level of compensatory arcs as well. The authors come to the conclusion on the pathogenetical role of the muscular dysbalance in the genesis of scoliotic deformation.