ABSTRACT
AIM: To review the incidence, timing, and outcome of infectious enteritis after intestinal transplantation (IT). METHOD: A retrospective review of all patients undergoing IT at a single institution between 1991 and 2003 was analyze with standard statistical tools. RESULTS: Among 33 IT recipients, 13 (39%) developed 20 culture- or biopsy-proven episodes of infectious enteritis. The recipient demographics were 77% men and median age 2.6 years. Infections were diagnosed at a median of 76 days (32 to 1800) after IT. There were 14 viral (CMV one, rotavirus eight, adenovirus four, EBV one, three bacterial (Clostridium difficile), and three other infections (Giardia lamblia one, cryptosporidium two). Complete resolution was achieved in 17 (94%) infectious after appropriate antimicrobial or conservative therapy. Interestingly, there were six rejection episodes following infectious enteritis. Grafts were lost to rejection after rotaviral enteritis (n = 1) and adenoviral enteritis misdiagnosed as rejection (n = 1). Patient and graft survival were not adversely affected by infections. CONCLUSIONS: Infectious enteritis occurs frequently after IT. Viral agents are the cause in two-thirds of cases. With supportive care and appropriate treatment, resolution is possible in the majority of cases. Differentiating rejection and infection by histopathology can be difficult.
Subject(s)
Bacterial Infections/epidemiology , Enteritis/epidemiology , Intestines/transplantation , Virus Diseases/epidemiology , Adult , Child , Female , Humans , Intestines/microbiology , Male , Postoperative Complications/microbiology , Postoperative Complications/virology , Retrospective Studies , Time Factors , Treatment OutcomeSubject(s)
Ear Neoplasms/pathology , Papilloma/pathology , Tympanic Membrane/pathology , Adult , Audiometry , Ear Neoplasms/diagnosis , Humans , Male , Papilloma/diagnosisABSTRACT
A protocol for assessment of biological hazard from ultraviolet radiation sources was developed. The protocol utilized both a ultraviolet radiation spectroradiometer and a broadband ultraviolet radiation meter for the determination of the erythemally effective irradiance and the actinic irradiance. A 250 W tungsten halogen lamp operating at 9.5 A was tested with this protocol. It was found that the erythemally effective irradiance varied from 41 microW cm(-2) at 10 cm to 1.5 microW cm(-2) at 50 cm. In the same range of distances, the actinic irradiance decreased from 23 to 0.5 microW cm(-2). The irradiance from the source was uniform within 30 degrees about the line perpendicular to the axis of the filament. Using the recommendation of the Australian radiation protection agency, the National Health and Medical Research Council, the maximum allowable exposure time at the distance of 50 cm in the direction perpendicular to the axis of the filament was about 33.3 minutes.
Subject(s)
Erythema/etiology , Photosensitivity Disorders/etiology , Radiodermatitis/etiology , Tungsten/adverse effects , Humans , Radiometry/methods , Ultraviolet Rays/adverse effectsABSTRACT
Between 1966 and 1981, 812 proximal interphalangeal joints were reconstructed by the senior author using the flexible silicone rubber implant resection arthroplasty method. Within this series, a group of 182 patients with 424 proximal interphalangeal joint implants were available for a detailed clinical and roentgenographic review. Increased motion in a more functional arc with good pain relief and a favorable bone response pattern were noted in most cases after surgery. Complications were rare and included implant dislocation or fracture, recurrence of deformity, and infection. The highest complication rate was noted in implant reconstructions performed to correct rheumatoid swan-neck deformities.
