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1.

Cephapirin concentrations in prostatic and seminal vesicle tissues.

Rubi, R; Galan, H M.

Int J Clin Pharmacol Biopharm ; 17(2): 87-9, 1979 Feb.

Article in English | MEDLINE | ID: mdl-422307

ABSTRACT

A 15 min i.v. infusion supplying either 1 or 2 g of sodium cephapirin was administered preoperatively to patients about to undergo either retropubic or transvesical prostatectomy. Tissue samples were obtained 30 min after the end of the infusion. Blood samples were obtained immediately before the start of the infusion and 30 min after the end of it. Cephapirin levels in the blood averaged 25.9 +/- 4.0 microgram/ml after the 1 g dose and 47.5 +/- 5.6 microgram/ml after the 2 g dose. Drug levels in prostatic tissue averaged 24.5 +/- 7.1 and 25.8 +/- 4.4 microgram/g for the 1 and 2 g doses, respectively. Levels in tissue taken from the seminal vesicle, often the focus of infection in bacterial prostatitis, averaged 12.5 +/- 2.3 and 44.8 +/- 14.9 microgram/g for the 1 and 2 g doses, respectively. These results suggest that bactericidal levels of cephapirin against sensitive organisms can readily be achieved in the prostate and seminal vesicles.

Subject(s)

Cephalosporins/metabolism , Cephapirin/metabolism , Prostate/metabolism , Seminal Vesicles/metabolism , Adolescent , Adult , Aged , Cephapirin/blood , Humans , In Vitro Techniques , Male , Middle Aged , Time Factors

2.

Experimental urinary infection in rats: pregnancy outcome and its relationship to uterine contractility.

Sala, N L; Rubi, R A; Galán, H M; Bogetti, H N.

Am J Obstet Gynecol ; 117(2): 255-60, 1973 Sep 15.

Article in English | MEDLINE | ID: mdl-4580746

Subject(s)

Muscle Contraction , Pregnancy Complications, Infectious/physiopathology , Urinary Tract Infections/physiopathology , Uterus/physiopathology , Abortion, Spontaneous/etiology , Amniotic Fluid , Animals , Endotoxins/pharmacology , Escherichia coli Infections/physiopathology , Female , Humans , In Vitro Techniques , Lipopolysaccharides/pharmacology , Pregnancy , Pyelonephritis/physiopathology , Rats , Time Factors , Uterus/drug effects

3.

[Clinical evaluation of the different ways and dosage of administering sodium dicloxacillin]. / Evaluación clinica de la dicloxacilina sódica con diferentes regímenes de dosificación.

Mazzei, C M; Bellomo, J A; Gherardi, C R; Galan, H M.

Prensa Med Argent ; 57(3): 133-41, 1970 Mar 20.

Article in Spanish | MEDLINE | ID: mdl-5453821

Subject(s)

Oxazoles/administration & dosage , Penicillins/administration & dosage , Adolescent , Adult , Aged , Capsules , Child , Dicloxacillin/administration & dosage , Humans , Injections, Intramuscular , Liver Function Tests , Middle Aged , Osteomyelitis/drug therapy , Respiratory Tract Diseases/drug therapy , Skin Diseases/drug therapy , Urologic Diseases/drug therapy

4.

[Clinical evaluation of sodium dicloxacillin with different dosage levels]. / Evaluación clínica de la dicloxacilina sódica con diferentes régimenes de dosificación

Mazzei, C M; Andrés Bellomo, J; Gherardi, C R; Galán, H M.

Rev Clin Esp ; 116(5): 443-52, 1970 Mar 15.

Article in Spanish | MEDLINE | ID: mdl-5528061

Subject(s)

Bacterial Infections/drug therapy , Dicloxacillin/administration & dosage , Adolescent , Adult , Aged , Bacteria , Capsules , Child , Dicloxacillin/therapeutic use , Drug Evaluation , Female , Humans , Injections, Intramuscular , Male , Middle Aged , Sodium

5.

[Treatment of genitourinary and respiratory tract infections in adults with potassium hetacilline by oral therapy]. / Tratamento de infecções das vias geniturinárias e respiratórias, em adultos, com hetacilina potássica por via oral.

Zelasco, J F; Rivelli, R; Lipke, E; Galán, H M.

Hospital (Rio J) ; 77(1): 57-68, 1970 Jan.

Article in Portuguese | MEDLINE | ID: mdl-5310004

Subject(s)

Respiratory Tract Infections/drug therapy , Thiazoles/administration & dosage , Urinary Tract Infections/drug therapy , Administration, Oral , Adolescent , Adult , Aged , Capsules , Female , Humans , Injections, Intramuscular , Male , Middle Aged , Potassium

6.

Evaluación clinica de la dicloxacilina sódica con diferentes regímenes de dosificación. / [Clinical evaluation of the different ways and dosage of administering sodium dicloxacillin]

Mazzei, C M; Bellomo, J A; Gherardi, C R; Galan, H M.

Prensa méd. argent ; 57(3): 133-41, 1970 Mar 20.

Article in Spanish | BINACIS | ID: bin-43753

7.

Evaluación clinica de la dicloxacilina sódica con diferentes regímenes de dosificación / [Clinical evaluation of the different ways and dosage of administering sodium dicloxacillin]

Mazzei, C M; Bellomo, J A; Gherardi, C R; Galan, H M.

Prensa méd. argent ; 57(3): 133-41, 1970 Mar 20.

Article in Spanish | LILACS-Express | BINACIS | ID: biblio-1168284

8.

["In vitro" activity of erythromycin]. / Actividad "in vitro" de la eritomicina.

Galan, H M; Blanco, C B; Tobar, E.

Prensa Med Argent ; 56(6): 272-5, 1969 Apr 11.

Article in Spanish | MEDLINE | ID: mdl-5810265

Subject(s)

Communicable Diseases/drug therapy , Erythromycin/pharmacology , Humans , In Vitro Techniques

9.

[Treatment of genitourinary infectious with a new antibiotic]. / Tratamento das infecções geniturinárias com um nôvo antibiótico.

García, A E; Muzio, A; Marzio, F; Galán, H M.

Rev Bras Med ; 26(1): 57, 1969 Jan.

Article in Portuguese | MEDLINE | ID: mdl-5788815

Subject(s)

Anti-Bacterial Agents/therapeutic use , Urologic Diseases/drug therapy , Humans

10.

Actividad [quot ]in vitro[quot ] de la eritomicina. / [[quot ]In vitro[quot ] activity of erythromycin]

Galan, H M; Blanco, C B; Tobar, E.

Prensa méd. argent ; 56(6): 272-5, 1969 Apr 11.

Article in Spanish | BINACIS | ID: bin-44798

11.

Actividad [quot ]in vitro[quot ] de la eritomicina / [[quot ]In vitro[quot ] activity of erythromycin]

Galan, H M; Blanco, C B; Tobar, E.

Prensa méd. argent ; 56(6): 272-5, 1969 Apr 11.

Article in Spanish | LILACS-Express | BINACIS | ID: biblio-1168014

12.

[A new antibiotic in the therapy of infected postoperative wounds and other hospital infections]. / Um nôvo antibiótico no tratamento de feridas pós-operatórias infectadas e de outras infecções hospitalares.

Brea, M M; Lange, W; Cervi, N; Brea, R; Galán, H M.

Hospital (Rio J) ; 74(6): 1973-5, 1968 Dec.

Article in Portuguese | MEDLINE | ID: mdl-5305619

Subject(s)

Cross Infection/drug therapy , Penicillins/therapeutic use , Surgical Wound Infection/drug therapy , Adult , Female , Humans , Male , Middle Aged , Postoperative Complications/drug therapy

13.

[Dicloxacillin in pyodermitis]. / Dicloxacilina en piodermitis.

Cordero, A; Trajtenberg, S; Galán, H M.

Prensa Med Argent ; 54(13): 599-603, 1967 May 26.

Article in Spanish | MEDLINE | ID: mdl-5605931

Subject(s)

Oxazoles/therapeutic use , Penicillins/therapeutic use , Pyoderma/drug therapy , Adolescent , Adult , Aged , Child , Child, Preschool , Dicloxacillin/therapeutic use , Female , Humans , Infant , Male , Middle Aged

14.

Dicloxacilina en piodermitis. / [Dicloxacillin in pyodermitis]

Cordero, A; Trajtenberg, S; Galán, H M.

Prensa méd. argent ; 54(13): 599-603, 1967 May 26.

Article in Spanish | BINACIS | ID: bin-42092

15.

Dicloxacilina en piodermitis / [Dicloxacillin in pyodermitis]

Cordero, A; Trajtenberg, S; Galán, H M.

Prensa méd. argent ; 54(13): 599-603, 1967 May 26.

Article in Spanish | LILACS-Express | BINACIS | ID: biblio-1166835

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