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1.
Pancreatic duct obstruction as a potential etiology of pancreatic adenocarcinoma: a clue from pancreas divisum.
Traverso, L W; Kozarek, R A; Simpson, T; Galagan, K A.
Am J Gastroenterol ; 88(1): 117-9, 1993 Jan.
Article in English | MEDLINE | ID: mdl-8420250

Subject(s)
Adenocarcinoma/etiology , Carcinoma in Situ/etiology , Pancreas/abnormalities , Pancreatic Ducts , Pancreatic Neoplasms/etiology , Constriction, Pathologic/complications , Female , Humans , Middle Aged
2.
Perianal Paget's disease: successful treatment with combined chemoradiotherapy. Report of a case.
Thirlby, R C; Hammer, C J; Galagan, K A; Travaglini, J J; Picozzi, V J.
Dis Colon Rectum ; 33(2): 150-2, 1990 Feb.
Article in English | MEDLINE | ID: mdl-2153511

ABSTRACT

A case of locally extensive perianal Paget's disease is presented. Initial wide local excision, guided by frozen sections, was inadequate. Multiple punch biopsies subsequently revealed extensive circumferential involvement of the anoderm by Paget's disease, making wide local excision difficult. Therefore, the patient was treated with combined chemoradiotherapy (5000 cGy, 5-fluorouracil, and mitomycin C). Fourteen months after treatment, the patient had a complete response.


Subject(s)
Anus Neoplasms/drug therapy , Anus Neoplasms/radiotherapy , Paget Disease, Extramammary/drug therapy , Paget Disease, Extramammary/radiotherapy , Aged , Anus Neoplasms/pathology , Combined Modality Therapy , Fluorouracil/therapeutic use , Humans , Male , Mitomycin , Mitomycins/therapeutic use , Paget Disease, Extramammary/pathology , Radiotherapy Dosage
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