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1.
JACC Case Rep ; 3(17): 1836-1841, 2021 Dec 01.
Article in English | MEDLINE | ID: mdl-34917964

ABSTRACT

Acupuncture is generally considered safe; however, cardiac complications can occur. We describe a case of refractory pericarditis requiring transvenous extraction of an acupuncture needle from within the right ventricular cavity. (Level of Difficulty: Intermediate.).

3.
Clin Cardiol ; 43(2): 156-162, 2020 Feb.
Article in English | MEDLINE | ID: mdl-31840834

ABSTRACT

As the population ages, clinicians will encounter a growing number of nonagenarians suffering from severe aortic stenosis who may be candidates for transcatheter aortic valve replacement (TAVR). By virtue of a healthy survivor effect or a referral bias, these patients may paradoxically have greater resilience and fewer comorbidities than their octogenarian counterparts. They tend to, on average, tolerate the TAVR procedure quite well with low in-hospital and 1-year mortality rates of 5.5% and 23%, respectively. Appropriate patient selection should consider individualized estimates of procedural risk, potential for functional recovery and for improved quantity and quality of life. Frailty is much more revealing than chronological age, and it can be measured by brief tools such as the Essential Frailty Toolset. Ultimately, the process of shared decision-making is paramount to ensure that the course of action is patient-centered and balances the procedure's expected risks and benefits with the nonagenarian's preferences and values.


Subject(s)
Aortic Valve Stenosis/surgery , Aortic Valve/pathology , Aortic Valve/surgery , Calcinosis/surgery , Transcatheter Aortic Valve Replacement , Age Factors , Aged, 80 and over , Aortic Valve/diagnostic imaging , Aortic Valve/physiopathology , Aortic Valve Stenosis/diagnostic imaging , Aortic Valve Stenosis/mortality , Aortic Valve Stenosis/physiopathology , Calcinosis/diagnostic imaging , Calcinosis/mortality , Calcinosis/physiopathology , Clinical Decision-Making , Comorbidity , Frail Elderly , Frailty/diagnosis , Frailty/mortality , Frailty/physiopathology , Health Status , Hemodynamics , Humans , Patient Selection , Quality of Life , Recovery of Function , Risk Assessment , Risk Factors , Transcatheter Aortic Valve Replacement/adverse effects , Transcatheter Aortic Valve Replacement/mortality , Treatment Outcome
4.
CJC Open ; 1(5): 231-237, 2019 Sep.
Article in English | MEDLINE | ID: mdl-32159114

ABSTRACT

BACKGROUND: Cerebral thromboembolism is a potentially devastating complication of atrial fibrillation (AF) and atrial flutter (AFl). The use of transesophageal echocardiogram (TEE) before electrophysiological procedures in anticoagulated patients is variable. Our objective was to determine the incidence and identify predictors of intracardiac left atrial appendage (LAA) thrombus on TEE in patients with AF/AFl before electrical cardioversion or ablation. METHODS: We reviewed TEEs of 401 patients undergoing an electrical cardioversion, AF, or AFl ablation from April 2013 to September 2015 at the McGill University Health Center. Clinical and echocardiographic variables were collected at the time of the TEE and follow-up visits. Multivariate logistic regression was used to determine predictors of LAA thrombus. RESULTS: Of 401 patients, 11.2% had LAA thrombus on TEE. The majority (87%) of patients were anticoagulated for at least 3 weeks before the TEE. The incidence of LAA thrombus was 21% (23/110) in patients taking warfarin vs 6.4% (15/236) in patients taking direct oral anticoagulants. Multivariate analysis identified prior stroke (odds ratio [OR], 2.7; 95% confidence interval [CI], 1.1-6.9) and heart failure (OR, 2.2; 95% CI, 1.0-4.7) as predictors of thrombus, whereas direct oral anticoagulant use (OR, 0.4; 95% CI, 0.2-0.8) was associated with reduced odds of thrombus. CONCLUSIONS: LAA thrombus was identified in a significant proportion of patients undergoing TEE before cardioversion or ablation of AF/AFl despite preprocedural anticoagulation. Patients at increased risk of LAA thrombus (heart failure and prior stroke) may benefit from TEE before cardioversion, AF, or AFl ablation.


INTRODUCTION: La thromboembolie cérébrale est une complication potentiellement dévastatrice de la fibrillation auriculaire (FA) et du flutter auriculaire. L'utilisation de l'échocardiographie transœsophagienne (ETO) avant les interventions en électrophysiologie chez les patients anticoagulés est variable. Notre objectif était de déterminer la fréquence et les prédicteurs des thrombi intracardiaques dans l'appendice auriculaire gauche (AAG) à l'ETO chez les patients atteints de FA ou de flutter auriculaire avant de procéder à une cardioversion électrique ou à une ablation. MÉTHODES: Nous avons passé en revue les ETO de 401 patients qui avaient subi une cardioversion électrique, ou une ablation de la FA ou du flutter auriculaire entre avril 2013 et septembre 2015 au Centre universitaire de santé McGill. Nous avons recueilli les variables cliniques et échocardiographiques au moment de l'ETO et des visites de suivi. Nous avons utilisé la régression logistique multivariée pour déterminer les prédicteurs de thrombus dans l'AAG. RÉSULTATS: Parmi les 401 patients, 11,2 % avaient un thrombus dans l'AAG à l'ETO. La majorité (87 %) des patients étaient anticoagulés au moins 3 semaines avant l'ETO. La fréquence des thrombus dans l'AAG était de 21 % (23/110) chez les patients qui prenaient de la warfarine vs 6,4 % (15/236) chez les patients qui prenaient des anticoagulants oraux directs. L'analyse multivariée a permis d'établir que l'accident vasculaire cérébral (AVC) antérieur (ratio d'incidence approché [RIA], 2,7; intervalle de confiance [IC] à 95 %, 1,1-6,9) et l'insuffisance cardiaque (RIA, 2,2; IC à 95 %, 1,0-4,7) étaient des prédicteurs de thrombus, alors que l'utilisation d'anticoagulants oraux directs (RIA, 0,4; IC à 95 %, 0,2-0,8) était associée une probabilité moindre de thrombus. CONCLUSIONS: Une proportion importante de patients qui avaient subi l'ETO avant la cardioversion, ou l'ablation de la FA ou du flutter auriculaire avaient un thrombus dans l'AAG en dépit de l'anticoagulation avant l'intervention. Les patients exposés à un risque accru de thrombus dans l'AAG (insuffisance cardiaque et AVC antérieur) peuvent bénéficier de l'ETO avant la cardioversion, ou l'ablation de la FA ou du flutter auriculaire.

6.
Surg Endosc ; 29(12): 3485-90, 2015 Dec.
Article in English | MEDLINE | ID: mdl-25673348

ABSTRACT

INTRODUCTION: The purpose of this study was to determine the proportion of symptomatic recurrence following initial non-operative management of gallstone disease in the elderly and to test possible predictors. METHODS: This is a single institution retrospective chart review of patients 65 years and older with an initial hospital visit (V1) for symptomatic gallstone disease, over a 4-year period. Patients with initial "non-operative" management were defined as those without surgery at V1 and without elective surgery at visit 2 (V2). Baseline characteristics included age, sex, Charlson comorbidity index (CCI), diagnosis, and interventions (ERCP or cholecystostomy) at V1. Outcomes assessed over 1 year were as follows: recurrence (any ER/admission visit following V1), surgery, complications, and mortality. A survival analysis using a Cox proportional hazards model was performed to assess predictors of recurrence. RESULTS: There were 195 patients initially treated non-operatively at V1. Mean age was 78.3 ± 7.8 years, 45.6% were male, and the mean CCI was 2.1 ± 1.9. At V1, 54.4% had a diagnosis of biliary colic or cholecystitis, while 45.6% had a diagnosis of cholangitis, pancreatitis, or choledocholithiasis. 39.5% underwent ERCP or cholecystostomy. Excluding 10 patients who died at V1, 31.3% of patients had a recurrence over the study period. Among these, 43.5% had emergency surgery, 34.8% had complications, and 4.3% died. Median time to first recurrence was 2 months (range 6 days-4.8 months). Intervention at V1 was associated with a lower probability of recurrence (HR 0.3, CI [0.14-0.65]). CONCLUSION: One-third of elderly patients will develop a recurrence following non-operative management of symptomatic biliary disease. These recurrences are associated with significant rates of emergency surgery and morbidity. Percutaneous or endoscopic therapies may decrease the risk of recurrence.


Subject(s)
Choledocholithiasis/therapy , Gallstones/therapy , Aged , Aged, 80 and over , Cholangiopancreatography, Endoscopic Retrograde/statistics & numerical data , Cholangitis/surgery , Cholecystitis/surgery , Cholecystostomy/statistics & numerical data , Choledocholithiasis/complications , Choledocholithiasis/mortality , Female , Gallstones/complications , Gallstones/mortality , Gastrointestinal Diseases/surgery , Humans , Male , Pancreatitis/surgery , Proportional Hazards Models , Recurrence , Retrospective Studies , Survival Analysis
7.
Eur Heart J ; 36(21): 1306-27, 2015 Jun 01.
Article in English | MEDLINE | ID: mdl-25265974

ABSTRACT

AIMS: A comprehensive description of transcatheter heart valve (THV) failure has not been performed. We undertook a systematic review to investigate the aetiology, diagnosis, management, and outcomes of THV failure. METHODS AND RESULTS: The systematic review was performed in accordance with the PRISMA guidelines using EMBASE, MEDLINE, and Scopus. Between December 2002 and March 2014, 70 publications reported 87 individual cases of transcatheter aortic valve implantation (TAVI) failure. Similar to surgical bioprosthetic heart valve failure, we observed cases of prosthetic valve endocarditis (PVE) (n = 34), structural valve failure (n = 13), and THV thrombosis (n = 15). The microbiological profile of THV PVE was similar to surgical PVE, though one-quarter had satellite mitral valve endocarditis, and surgical intervention was required in 40% (75% survival). Structural valve failure occurred most frequently due to leaflet calcification and was predominantly treated by redo-THV (60%). Transcatheter heart valve thrombosis occurred at a mean 9 ± 7 months post-implantation and was successfully treated by prolonged anticoagulation in three-quarters of cases. Two novel causes of THV failure were identified: late THV embolization (n = 18); and THV compression (n = 7) following cardiopulmonary resuscitation (CPR). These failure modes have not been reported in the surgical literature. Potential risk factors for late THV embolization include low prosthesis implantation, THV undersizing/underexpansion, bicuspid, and non-calcified anatomy. Transcatheter heart valve embolization mandated surgery in 80% of patients. Transcatheter heart valve compression was noted at post-mortem in most cases. CONCLUSION: Transcatheter heart valves are susceptible to failure modes typical to those of surgical bioprostheses and unique to their specific design. Transcatheter heart valve compression and late embolization represent complications previously unreported in the surgical literature.


Subject(s)
Aortic Valve Stenosis/surgery , Heart Valve Prosthesis , Prosthesis Failure/adverse effects , Transcatheter Aortic Valve Replacement , Aged , Aged, 80 and over , Anti-Infective Agents/therapeutic use , Embolism/etiology , Endocarditis/drug therapy , Endocarditis/etiology , Endocarditis/prevention & control , Female , Graft Occlusion, Vascular/etiology , Gram-Positive Bacterial Infections/diagnosis , Gram-Positive Bacterial Infections/drug therapy , Histoplasmosis/diagnosis , Histoplasmosis/drug therapy , Humans , Male , Middle Aged , Risk Factors
8.
Surg Endosc ; 25(1): 55-61, 2011 Jan.
Article in English | MEDLINE | ID: mdl-20512508

ABSTRACT

BACKGROUND: This study aimed to describe the differences in the management of symptomatic gallstone disease within different elderly groups and to evaluate the association between older age and surgical treatment. METHODS: This single-institution retrospective chart review included all patients 65 years old and older with an initial hospital visit for symptomatic gallstone disease between 2004 and 2008. The patients were stratified into three age groups: group 1 (age, 65-74 years), group 2 (age, 75-84 years), and group 3 (age, ≥ 85 years). Patient characteristics and presentation at the initial hospital visit were described as well as the surgical and other nonoperative interventions occurring over a 1-year follow-up period. Logistic regression was performed to assess the effect of age on surgery. RESULTS: Data from 397 patient charts were assessed: 182 in group 1, 160 in group 2, and 55 in group 3. Cholecystitis was the most common diagnosis in groups 1 and 2, whereas cholangitis was the most common diagnosis in group 3. Elective admissions to a surgical ward were most common in group 1, whereas urgent admissions to a medical ward were most common in group 3. Elective surgery was performed at the first visit for 50.6% of group 1, for 25.6% of group 2, and for 12.7% of group 3, with a 1-year cumulative incidence of surgery of 87.4% in group 1, 63.5% in group 2, and 22.1% in group 3. Inversely, cholecystostomy and endoscopic retrograde cholangiopancreatography (ERCP) were used more often in the older groups. Increased age (odds ratio [OR], 0.87; 95% confidence interval [CI], 0.84-0.91) and the Charlson Comorbidity Index (OR, 0.80; 95% CI, 0.69-0.94) were significantly associated with a decreased probability of undergoing surgery within 1 year after the initial visit. CONCLUSION: Even in the elderly population, older patients presented more frequently with severe disease and underwent more conservative treatment strategies. Older age was independently associated with a lower likelihood of surgery.


Subject(s)
Age Factors , Cholecystectomy/statistics & numerical data , Cholelithiasis/surgery , Disease Management , Aged , Aged, 80 and over , Cholangiopancreatography, Endoscopic Retrograde/statistics & numerical data , Cholangitis/surgery , Cholecystectomy, Laparoscopic/statistics & numerical data , Cholecystitis/surgery , Comorbidity , Elective Surgical Procedures , Emergencies , Emergency Service, Hospital/statistics & numerical data , Female , Follow-Up Studies , Hospitals, General/statistics & numerical data , Humans , Male , Patient Admission/statistics & numerical data , Quebec , Retrospective Studies
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