ABSTRACT
This controlled prospective study included 40 children (18 boys and 22 girls) hospitalized for the treatment of acute suppurative otitis media. Mean age of the patients was 4.5 years. Their condition was evaluated after cessation of purulent discharge and closure of perforation while acoustic impedancometry still revealed the presence of exudate in the tympanum. The treatment included administration of nasal decongestants, systemic antibacterial therapy, sanation of the nasal and pharyngonasal cavities by transposition or puncture of maxillary sinuses. Some patients (study group) were given sinupret in age-adjusted doses. Signs of exudates disappeared within a mean of 4.2 days after the onset of therapy compared with 7.7 days in the control group (p<0.01). It is concluded that the inclusion of sinupret in the combined treatment of acute suppurative otitis media promotes rapid and efficacious sanation of the tympanic cavity and hearing restoration.
