ABSTRACT
BACKGROUND: Grape seed pomace is a valuable by-product from winery/oil extraction industries and a potential source of bioactive compounds. Hot water extraction is the most widely used technology for polysaccharide recovery from plant and seed sources. To obtain an antioxidant fiber-rich extract (AFE) from defatted grape seed pomace, seed:water ratio (1:10-1:20) and extraction temperature (70-90 °C) effects on extraction yield, total sugars, total phenolic compounds and condensed tannins were investigated. RESULTS: The best extraction results were achieved at the highest seed:water ratio and temperature. At these conditions, the extraction yield and total sugar content of the freeze-dried AFE were 100.1 g kg-1 and 725.3 g kg-1 , respectively. The AFE presented high total phenolic content (16.2 g GAE kg-1 ), condensed tannins (515.1 mg CAT kg-1 ), soluble (219.1 g kg-1 ) and insoluble fibers (132.4 g kg-1 ), besides protein (171.1 g kg-1 ) and ash (152.6 g kg-1 ). The antioxidant capacity of the AFE was 382.7, 823.7 and 1439.4 µmol Trolox g-1 for DPPH, ABTS and ORAC methods. CONCLUSION: The AFE was shown to be not only an interesting source of fiber with antioxidant capacity, which could become a potential foodstuff, but also an ecofriendly and sustainable alternative to use grape seed pomace. © 2019 Society of Chemical Industry.
Subject(s)
Antioxidants/analysis , Dietary Fiber/analysis , Plant Extracts/analysis , Seeds/chemistry , Vitis/chemistry , Waste Products/analysis , Fruit/chemistry , Phenols/analysis , Proanthocyanidins/analysisABSTRACT
Após a observaçäo da realidade na Unidade Básica de Saúde Parque das Indústrias do Município de Londrina, os autores verificaram, em vários levantamentos realizados, a deficiência no controle e distribuiçäo de medicamentos, bem como a falta dos mesmos para usuários desta Unidade. Portanto, objetivou-se analisar a sistemática de distribuiçäo e prescriçäo de medicamentos desses serviços nas Unidades Básicas de Saúde da Regiäo Sul, além de propor um esquema de controle para tal distribuiçäo. Para atingir tal objetivo, foram levantados dados através da aplicaçäo de questionários para 17 médicos e dentistas, 25 auxiliares de enfermagem, além de 51 pacientes que foram submetidos a consultas médicas ou odontológicas nas citadasUnidades Básicas de Saúde (UBS). Com a mesma finalidade, também foram realizadas entrevistas com a chefia da divisäo de unidades ambulatoriais da Secretaria Municipal de Saúde e Centrofarma do Serviço de Saúde do Município
