Subject(s)
HIV Infections/complications , Thrombosis/etiology , Anti-HIV Agents/therapeutic use , Anticoagulants/therapeutic use , Antiretroviral Therapy, Highly Active , Female , HIV Infections/drug therapy , Heparin/therapeutic use , Humans , Middle Aged , Thrombosis/diagnostic imaging , Thrombosis/drug therapyABSTRACT
No disponible
Subject(s)
Humans , Angiotensin-Converting Enzyme Inhibitors/pharmacokinetics , Hydroxychloroquine/pharmacokinetics , Coronavirus Infections/drug therapy , Pneumonia, Viral/drug therapy , Cardiovascular Agents/adverse effects , Severe Acute Respiratory Syndrome/drug therapy , Severe acute respiratory syndrome-related coronavirus/pathogenicity , Risk Factors , Comorbidity , Cardiotoxicity/prevention & control , Contraindications, Drug , Cardiovascular Diseases/drug therapySubject(s)
Coronavirus Infections/complications , Pneumonia, Viral/complications , Pulmonary Embolism/virology , Aged , Betacoronavirus , COVID-19 , Female , Humans , Lung/diagnostic imaging , Lung/pathology , Pandemics , Pulmonary Embolism/diagnostic imaging , SARS-CoV-2 , Tomography, X-Ray ComputedSubject(s)
Acute Coronary Syndrome/therapy , Adenosine Monophosphate/analogs & derivatives , Percutaneous Coronary Intervention , Platelet Aggregation Inhibitors/therapeutic use , Acute Coronary Syndrome/diagnostic imaging , Acute Coronary Syndrome/physiopathology , Adenosine Monophosphate/therapeutic use , Aged , Combined Modality Therapy , Electrocardiography , Female , HumansABSTRACT
Treatment of ST-elevation myocardial infarction has advanced tremendously over the past years; this development has proven to be beneficial in reducing mortality and cardiovascular events. Clinical baseline factors remain the cornerstone of prognostic stratification. Tools for prognostic stratification after myocardial infarction are targeted at evaluating myocardial damage, left ventricular dysfunction, residual ischemia and electrical instability. Primary coronary angioplasty is the preferred therapeutic option because, when it can be performed expeditiously by an experienced team, has shown better clinical outcomes; nevertheless we have to pay attention to avoid procedure-related risks such as bleeding and contrast-induced nephropathy.
Subject(s)
Angioplasty, Balloon, Coronary , Coronary Angiography , Myocardial Infarction/diagnosis , Myocardial Infarction/therapy , Age Factors , Aged , Contrast Media/adverse effects , Electrocardiography , Female , Hemorrhage/complications , Humans , Hypotension/complications , Kidney Diseases/chemically induced , Male , Myocardial Contraction , Myocardial Infarction/diagnostic imaging , Myocardial Infarction/drug therapy , Myocardial Infarction/mortality , Myocardial Infarction/physiopathology , Prognosis , Randomized Controlled Trials as Topic , Risk Factors , Sex Factors , Tachycardia/complications , Time Factors , Treatment Outcome , Ventricular Dysfunction, LeftABSTRACT
Although a close relationship between haemorrheological disorders and thrombogenesis has been known for a long time, only the recent introduction of newly developed analytical techniques has allowed a precise assessment of the main haemorrheological parameters. The employment of these techniques in routine clinical practice has enabled, for instance, a more accurate investigation of the pathogenetic triggers underlying numerous thrombotic disorders affecting the cardiovascular system. A survey of the most exhaustive prospective studies shows that some haemorrheological parameters (e.g. plasma and blood viscosity) as well as their main determining factors (e.g. haematocrit and fibrinogen) are well defined independent cardiovascular risk factors. Nonetheless, further large scale studies are required to adequately dissect the relative contribution of both haemorrheological alterations and other thrombophilic factors in the pathogenesis of different cardiovascular diseases related to thrombotic disorders.