ABSTRACT
INTRODUCTION: Among the manifestations of Münchausen's syndrome, "neurological" forms may exist. OBSERVATION: We present the case of a patient presenting with urinary retention following treatment for urinary incontinence. The patient had injected himself with infected urine collected from his catheter, in order to create septicemia. COMMENTS: Nephritic colitis, false gall stones, addition of fecal matter or of food and saliva in the urine or the bladder, neurogenic bladder and urinary infections have all been reported as possible manifestations of Münchausen's syndrome. Diagnosis of this syndrome is often delayed and laborious, after repeated hospitalisations, examinations and often aggressive treatment. Its therapeutic management is difficult. Patients, despite proof, deny their deceit and refuse psychiatric care.
Subject(s)
Munchausen Syndrome/diagnosis , Urologic Diseases/diagnosis , Diagnosis, Differential , Female , Humans , Middle Aged , Munchausen Syndrome/psychology , Munchausen Syndrome/therapyABSTRACT
OBJECTIVE: We evaluated temporal 67gallium (Ga) uptake in temporal arteritis (TA) and the contribution of Ga scans to the diagnosis of TA. METHODS: Ga scans were performed prospectively in 19 patients with biopsy-proven TA and five TA patients with negative temporal artery biopsy. Controls were 18 elderly patients undergoing Ga scans for various inflammatory diseases. The temporal region of interest on head profiles was defined for comparison of uptake with a control parietal region of the same area. The Ga uptake ratio (GaUR) [(temporal region - parietal region)/parietal region] was evaluated for each temple by a computer and intra- and intergroup comparisons were made. RESULTS: GaUR was significantly higher in biopsy-proven TA patients (0.35+/-0.19) and biopsy-negative TA patients (0.31+/-0.03) than in controls (0.18+/-0.12) (P < 0.001), independently of recent temporal artery biopsy or short-duration steroid therapy. High GaUR (>0.4) had a 94% specificity and a 90% positive predictive value for TA diagnosis. After 6 months of steroid therapy, when patients were in remission, GaUR returned to baseline. CONCLUSION: Ga is specifically incorporated into the temporal area in TA patients which may be due to the granulomatous vasculitic process. Ga uptake ceases during remission. A high GaUR may contribute to TA diagnosis in temporal artery biopsy-negative patients and its role in the diagnosis of other localizations of the disease requires further evaluation.
Subject(s)
Gallium Radioisotopes , Giant Cell Arteritis/diagnostic imaging , Adrenal Cortex Hormones/therapeutic use , Aged , Aged, 80 and over , Female , Giant Cell Arteritis/drug therapy , Humans , Inflammation/diagnostic imaging , Male , Middle Aged , Prospective Studies , Radionuclide ImagingSubject(s)
Candidiasis , Discitis/microbiology , Adolescent , Adult , Aged , Aged, 80 and over , Humans , Middle AgedSubject(s)
Peritonitis/etiology , Pneumococcal Infections/complications , Salpingitis/complications , Adult , Amoxicillin/therapeutic use , Ceftriaxone/therapeutic use , Cephalosporins/therapeutic use , Female , Follow-Up Studies , Humans , Penicillins/therapeutic use , Peritonitis/diagnosis , Peritonitis/drug therapy , Pneumococcal Infections/diagnosis , Pneumococcal Infections/drug therapy , Salpingitis/diagnosis , Time Factors , Tomography, X-Ray ComputedSubject(s)
Bartonella henselae/classification , Cat-Scratch Disease/microbiology , Abscess/microbiology , Adult , Animals , Azithromycin/therapeutic use , Bartonella henselae/isolation & purification , Cat-Scratch Disease/complications , Cat-Scratch Disease/drug therapy , Cats , Hepatolenticular Degeneration/complications , Humans , Male , Serotyping , Siphonaptera/microbiologySubject(s)
Antidepressive Agents/adverse effects , Antihypertensive Agents/therapeutic use , Antimanic Agents/adverse effects , Lithium Carbonate/adverse effects , Losartan/therapeutic use , Aged , Ataxia/chemically induced , Bipolar Disorder/drug therapy , Confusion/chemically induced , Drug Interactions , Dysarthria/chemically induced , Female , Humans , Hypertension/drug therapy , Lithium Carbonate/bloodABSTRACT
Discovery on a protein electrophoregram of a bisalbuminemia can orientate according to its migration fast or slow to an hereditary mutation of an amino acid, or an acquired form by excess of beta lactamines due to renal insufficiency or by the rupture of a pancreatic pseudocyst in the peritoneum. This is this late mechanism that we report in this case of bisalbuminemia related to an opened pancreatic pseudocyst secondary to an adenoma of the parathyroid gland.
Subject(s)
Hyperparathyroidism/complications , Pancreatic Fistula/etiology , Pancreatic Pseudocyst/complications , Serum Albumin/analysis , Blood Protein Electrophoresis , Chronic Disease , Fistula/etiology , Humans , Hyperparathyroidism/blood , Male , Middle Aged , Pancreatic Fistula/blood , Pancreatic Pseudocyst/blood , Pancreatitis/etiology , Peritoneal Diseases/etiologyABSTRACT
We report two cases of bone and joint amyloidosis involvement related to plasma cell dyscrasia. The radiographic appearances mimic numerous benign or malignant diseases. MR imaging shows a diffuse low signal in T1 and an heterogeneous low or mild low signal in T2 weighted spin-echo sequence.
Subject(s)
Amyloidosis/complications , Dysgammaglobulinemia/complications , Joint Diseases/blood , Spinal Diseases/diagnostic imaging , Aged , Female , Humans , Joint Diseases/complications , Joint Diseases/diagnostic imaging , Magnetic Resonance Imaging , Male , Middle Aged , Plasmacytoma/diagnosis , Radiography, Thoracic , Spine/diagnostic imagingSubject(s)
Abdomen, Acute/etiology , Antiphospholipid Syndrome/complications , Mesenteric Veins , Thrombosis/complications , Aged , Humans , MaleABSTRACT
We report the second case of intraalveolar haemorrhage associated with an autoimmune thyrotoxicosis. While intraalveolar haemorrhage was not recurrent since 7 years with corticosteroid therapy, a relapse occurred when we began the treatment for an autoimmune thyrotoxicosis. We discuss the link between intraalveolar haemorrhage and autoimmune thyrotoxicosis or its treatment.
Subject(s)
Graves Disease/complications , Hemorrhage/etiology , Lung Diseases/etiology , Adult , Female , Follow-Up Studies , Graves Disease/drug therapy , Hemosiderosis/etiology , Hemosiderosis/immunology , Humans , RecurrenceSubject(s)
Tuberculosis, Pulmonary/complications , Uveitis, Anterior/etiology , Adult , Female , HumansABSTRACT
A 27 year-old man who underwent an intestinal segmental resection for small bowel perforation was hospitalized for chronic abdominal pain with weight loss. Coeliac and mesenteric stenosis was diagnosed and laparotomy was performed. Histologic findings were consistent with Buerger's disease. One month later, he developed intermittent claudication of the left leg, and 8 years later amputation of a toe was performed. Since 1956, 25 cases of abdominal Buerger's disease has been reported in the literature. In eight cases, intestinal involvement inaugurated the disease. The clinical presentation can be various: chronic abdominal pain, mesenteric infartus, occlusion, perforation. Small bowel, colon and rectum can be concerned. The literature points out a mortality rate of 25% in intestinal Buerger's disease, contrasting with a mortality rate of 4% in peripheral forms of the disease. Although rare, intestinal form of Buerger's disease should be diagnosed early, because of its high mortality rate. Doppler of mesenteric arteries may contribute to the early diagnosis.
Subject(s)
Intestinal Perforation/etiology , Jejunal Diseases/etiology , Thromboangiitis Obliterans/complications , Adult , Humans , Male , Prognosis , Thromboangiitis Obliterans/diagnosis , Time FactorsSubject(s)
Behcet Syndrome/complications , Epididymitis/etiology , Adult , Behcet Syndrome/ethnology , France , Humans , Male , RecurrenceSubject(s)
Pancreatic Diseases/etiology , Tuberculosis, Lymph Node/diagnosis , Adult , Humans , MaleABSTRACT
Pneumocystis carinii pneumonia (PCP) is a well known opportunistic infection in Systemic Lupus Erythematosus (SLE) patients with lymphopenia and treated with corticosteroid or cytotoxics agents. We report a new case of PCP in an untreated SLE with severe lymphopenia. We discuss the origin of lymphopenia in SLE, lymphopenia as a risk factor of Pneumocystis carinii infection, and safety precautions to take.