ABSTRACT
This article reports results of the in vitro study for potential evaluation of the laser-induced fluorescence spectroscopy in the differentiation between normal and neoplastic human breast tissue. A coumarine dye laser pumped by nitrogen laser generated an excitation light centered at 458 nm. In order to collect the fluorescence signal was used an optical fiber catheter coupled to a spectrometer and CCD detector. Fluorescence spectra were recorded from normal and neoplastic (benign and malignant) human breast tissue, adding up 94 different areas. The discrimination between normal and neoplasm groups reach a sensitivity and specificity of 100%.
Subject(s)
Breast Neoplasms/diagnosis , Breast Neoplasms/pathology , Lasers , Spectrometry, Fluorescence/instrumentation , Breast Diseases/diagnosis , Breast Diseases/pathology , Diagnosis, Differential , Female , Humans , Sensitivity and SpecificityABSTRACT
O espectro de potência e a coerência inter-hemisférica foram estimados para segmentos dos padrões do ciclo sono-vigélia Low Voltage Irregular, Misto e High Voltage Slow. Diferenças significativas entre estes padrões foram encontradas, através da ANOVA, em uma larga faixa de frequência, principalmente para o espectro de potência até 15 Hz.