[The role of thyroid hypofunction in development of metabolic syndrome].

AIM: To study the role of hypothyroidism and concomitant obesity in the development of metabolic syndrome (MS). MATERIAL AND METHODS: We examined 60 women suffering from obesity and hypothyroidism (TTH 22.24 +/- 4.031). We studied lipid spectrum, carbohydrate metabolism, BP and insulin resistance, fat tissue distribution, exercise tolerance. RESULTS: According to IDF (2005) criteria the women had: metabolic syndrome (83.4%), newly diagnosed hypothyroidism (95%), decompensated hypothyroidism (90%), subclinical hypothyroidism (65%) after six-month replacement therapy with L-T4 MS symptoms declined. CONCLUSION: Abnormally high level of TSH may be a component of metabolic syndrome.