ABSTRACT
Acquired haemophilia A (AHA) is a rare autoimmune disorder resulting from antibodies against coagulation factor VIII. AHA causes severe, unexpected bleeding which may be life-threatening and should be considered when a patient with no previous history of bleeding presents with spontaneous bleeding and a prolonged APTT. This case report describes onset of AHA of a 75-year-old male who was admitted to Vejle Hospital with acute need for intubation due to breathing and swallowing problems caused by supraglottic haematoma. The case was complicated by anticoagulant treatment with rivaroxaban.
Subject(s)
Autoimmune Diseases , Hemophilia A , Male , Humans , Aged , Hemophilia A/complications , Hemophilia A/diagnosis , Hematoma/diagnosisABSTRACT
BACKGROUND: The Voice Handicap Index 30 (VHI-30) is a much-used voice specific quality of life questionnaire. A shortened 10 item version has been developed by eliminating redundant items using item analyses. This is the first Danish translation of the VHI-10. OBJECTIVES: To evaluate the psychometric properties of the Danish VHI-10 questionnaire. STUDY DESIGN: Cross-sectional survey study. METHODS: A Danish translation of the VHI-10 was answered by 72 patients with voice disorders of different etiology (neurogenic, functional, and structural) and by a control group of 94 vocally healthy individuals. Thirty-two patients and 68 controls participated in a test-retest reliability analysis. The internal consistency, test-retest reliability, and clinical validity were assessed. RESULTS: Excellent internal consistency was found in the patient group with a Cronbach's α of >0.90. In the control group the internal consistency was good with a Cronbach's α of 0.88. Test-retest reliability was good with intra class correlation coefficient of 0.94 (95% confidence interval [95%CI]: 0.88-0.97) for patients and 0.82 (95%CI: 0.73-0.89) for the control group. This indicates a sufficient reliability of the questionnaire. The correlation between the Danish VHI-10 score and the patient's perception of the severity of the voice disorder was 0.75 (P < 0.001) indicating good clinical validity of the Danish VHI-10. CONCLUSION: The newly translated Danish VHI-10 was validated and performs similar to the original VHI-10. It showed good internal consistency, test-retest reliability, and clinical validity. The questionnaire is preferably for use in patients with moderate to severe voice complaints as its ability to distinguish mild voice changes from healthy voices is limited. However, the questionnaire is capable of assessing patients' perception of the severity of their voice disorder and is available for use in daily practice and in research projects.
Subject(s)
Quality of Life , Voice Disorders , Cross-Sectional Studies , Denmark , Disability Evaluation , Humans , Reproducibility of Results , Severity of Illness Index , Surveys and Questionnaires , Voice Disorders/diagnosisABSTRACT
Dacryocystorhinostomy (DCR) is used for treating lacrimal duct obstruction and can be performed with an external (EXT) or an endoscopic (END) approach. In this case report a 70-year-old woman suffering from chronic epiphora had earlier been treated with exploration of the lacrimal duct with insertion of a silicone tube. Due to continuous epiphora the patient underwent END DCR revision surgery, where a 4-cm silicone tube was retrieved from the distal part of the lacrimal duct. If EXT DCR was used for revision surgery, most likely the silicone tube in the lacrimal duct would not have been found.
