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1.
J Ethn Subst Abuse ; 18(3): 387-401, 2019.
Article in English | MEDLINE | ID: mdl-29144881

ABSTRACT

Drug courts have been an important part of the criminal justice system since 1989. They continue to expand throughout the United States because nearly three decades of research has shown that they are more effective than other interventions, such as traditional probation. There is a pattern, though, in some drug courts where African Americans are less likely to graduate than their Caucasian counterparts. This qualitative study explores this phenomenon by asking African American participants (n = 31) their views on the most helpful aspects of drug court and how drug court could be more helpful in supporting them in graduating the program. Participants felt that the respect and compassion they received from the drug court judge and their case managers, as well as the camaraderie they developed with other participants, was an aspect of drug court that supported them in graduating the program. Next, participants felt that graduation rates would improve if drug court better supported them in gaining employment or sustaining the employment they already had. Implications for drug court practice are discussed.


Subject(s)
Black or African American/statistics & numerical data , Employment/statistics & numerical data , Jurisprudence , Substance-Related Disorders/rehabilitation , Adolescent , Adult , Black or African American/legislation & jurisprudence , Female , Humans , Male , United States , Young Adult
2.
Science ; 354(6309): 237-240, 2016 10 14.
Article in English | MEDLINE | ID: mdl-27708058

ABSTRACT

Zika virus (ZIKV) was identified as a cause of congenital disease during the explosive outbreak in the Americas and Caribbean that began in 2015. Because of the ongoing fetal risk from endemic disease and travel-related exposures, a vaccine to prevent viremia in women of childbearing age and their partners is imperative. We found that vaccination with DNA expressing the premembrane and envelope proteins of ZIKV was immunogenic in mice and nonhuman primates, and protection against viremia after ZIKV challenge correlated with serum neutralizing activity. These data not only indicate that DNA vaccination could be a successful approach to protect against ZIKV infection, but also suggest a protective threshold of vaccine-induced neutralizing activity that prevents viremia after acute infection.


Subject(s)
Immunogenicity, Vaccine , Vaccines, DNA/immunology , Viral Envelope Proteins/immunology , Viral Vaccines/immunology , Zika Virus Infection/prevention & control , Zika Virus/immunology , Animals , Antibodies, Neutralizing/blood , Antibodies, Neutralizing/immunology , Female , Macaca mulatta , Male , Mice , Vaccination , Viral Envelope Proteins/genetics , Viral Load/immunology , Viremia/immunology , Viremia/prevention & control , Zika Virus/genetics , Zika Virus Infection/virology
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