Comparación entre lidocaína tópica, intravenosa y en el interior del globo del tubo endotraqueal para disminuir la tos tras la extubación en la educción anestésica / Comparison of topical, intravenous, and intracuff lidocaine for reducing coughing after extubation during emergence from general anesthesia

OBJETIVOS: Comparar el efecto del uso tópico, intravenoso, así como en el interior del globo del tubo endotraqueal de la lidocaína para disminuir la tos en la educción anestésica.PACIENTES Y MÉTODOS: Se incluyeron pacientes deestado físico ASA I y II, mayores de 18 años de edad,programados para cirugía electiva bajo anestesia generalbalanceada con intubación orotraqueal, con unaduración de entre 60 y 120 minutos. Se distribuyeron alazar entre lidocaína intravenosa, tópica, en el interiordel globo del tubo endotraqueal o en el grupo control.Las variables numéricas se describieron utilizandomedia M y desviación estándar (M±DE) o mediana eintervalo intercuartilar [MD(25-75)] en dependencia dela distribución que mostrase. Las variables categóricasse describen con frecuencias (n) y porcentajes (%). Lascomparaciones entre múltiples grupos se realizaron conANOVA, prueba de Kruskal-Wallis o χ2 según correspondiera. Se consideró significancia estadística cuando P fue menor a 0,05.RESULTADOS: Se incluyeron 80 pacientes y se pudieronanalizar 78. La tos se presentó en 13 pacientes (65%) enel grupo control, en 5 (26,3%) en el grupo tópico, en 3(15,8%) en el grupo del globo y en 3 (16%) en el grupointravenoso (p < 0,05).CONCLUSIONES: La lidocaína intravenosa y en el interiordel globo del tubo endotraqueal disminuyen de unaforma estadísticamente significativa la incidencia de tosen la educción anestésica

OBJETIVOS: To compare the effect of topical, intravenous, and intracuff lidocaine on reducingcoughing during emergence from general anesthesia.PATIENTS AND METHODS: Patients with an ASA physicalstatus of I or II were enrolled if they were over 18 years of age and scheduled for elective surgery lasting between 60 and 120 minutes under balanced anesthesia withorotracheal intubation. Enrolled patients were randomlyassigned to one of 3 treatment groups (intravenouslidocaine, topical lidocaine, or intracuff lidocaine) or to the control group. Numerical variables were describedas mean (SD) or median and interquartile range,depending on distribution. Categorical variables weredescribed using frequencies (number) and percentages.Multiple-group comparisons were performed usinganalysis of variance, the Kruskal-Wallis test, or the χ2test, as appropriate. A level of P<.05 was considered tobe statistically significant.RESULTS: We enrolled 80 patients; data for 78 wereentered into analysis. Thirteen patients (65%) presentedcoughing in the control group, 5 (26.3%) in the topicallidocaine group, 3 (15.8%) in the intracuff group, and 3(16%) in the intravenous group (P<.05).CONCLUSIONS: Intravenous lidocaine and intracufflidocaine significantly reduce the incidence of coughing during emergence from anesthesia (AU)

[Comparison of topical, intravenous, and intracuff lidocaine for reducing coughing after extubation during emergence from general anesthesia]. / Comparación entre lidocaína tópica, intravenosa y en el interior del globo del tubo endotraqueal para disminuir la tos tras la extubación en la educción anestésica.

OBJECTIVE: To compare the effect of topical, intravenous, and intracuff lidocaine on reducing coughing during emergence from general anesthesia. PATIENTS AND METHODS: Patients with an ASA physical status of I or II were enrolled if they were over 18 years of age and scheduled for elective surgery lasting between 60 and 120 minutes under balanced anesthesia with orotracheal intubation. Enrolled patients were randomly assigned to one of 3 treatment groups (intravenous lidocaine, topical lidocaine, or intracuff lidocaine) or to the control group. Numerical variables were described as mean (SD) or median and interquartile range, depending on distribution. Categorical variables were described using frequencies (number) and percentages. Multiple-group comparisons were performed using analysis of variance, the Kruskal-Wallis test, or the chi2 test, as appropriate. A level of P < .05 was considered to be statistically significant. RESULTS: We enrolled 80 patients; data for 78 were entered into analysis. Thirteen patients (65%) presented coughing in the control group, 5 (263%) in the topical lidocaine group, 3 (15.8%) in the intracuff group, and 3 (16%) in the intravenous group (P < .05). CONCLUSIONS: Intravenous lidocaine and intracuff lidocaine significantly reduce the incidence of coughing during emergence from anesthesia.