1.
Semin Liver Dis
; 36(2): 181-6, 2016 05.
Article
in English
| MEDLINE
| ID: mdl-27172361
ABSTRACT
Acute-on-chronic liver failure (ACLF) represents a reversible syndrome associated with high short-term mortality, characterized by acute decompensation in patients with chronic liver disease and extrahepatic organ failure. Diagnosis and prognosis assessment is based on a newly developed diagnostic score, the Chronic Liver Failure Consortium Organ Failure score. Susceptibility to infections and systemic inflammation are typical triggers. The authors report a case in which a patient with alcohol-related cirrhosis was admitted to the hospital with acute decompensation and developed ACLF during hospitalization. This case led to an evaluation of the underlying process causing ACLF: infection versus acute alcoholic hepatitis.
Subject(s)
Acute-On-Chronic Liver Failure/diagnosis , Bacterial Infections/diagnosis , Hepatitis, Alcoholic/diagnosis , Organ Dysfunction Scores , Acute Kidney Injury/complications , Acute-On-Chronic Liver Failure/drug therapy , Acute-On-Chronic Liver Failure/etiology , Acute-On-Chronic Liver Failure/pathology , Administration, Intravenous , Anti-Bacterial Agents/administration & dosage , Diagnosis, Differential , Humans , Liver Cirrhosis, Alcoholic/complications , Male , Middle Aged , Radiography , Severity of Illness Index , Tomography, X-Ray Computed
2.
Inflamm Bowel Dis
; 17(11): E143-4, 2011 Nov.
Article
in English
| MEDLINE
| ID: mdl-21793127