ABSTRACT
BACKGROUND: Meniere disease (MD) is an inner ear disorder associated with comorbidities such as autoimmune diseases or migraine. This study describes clinical and cytokine profiles in MD according to the age of onset of the condition. METHODS: A cross-sectional study including 83 MD patients: 44 with early-onset MD (EOMD, <35 years old), and 39 with late-onset MD (LOMD, >50 years old), 64 patients with migraine and 55 controls was carried out. Clinical variables and cytokines levels of CCL3, CCL4, CCL18, CCL22, CXCL,1 and IL-1ß were compared among the different groups. RESULTS: CCL18 levels were higher in patients with migraine or MD than in controls. Elevated levels of IL-1ß were observed in 11.4% EOMD and in 10.3% LOMD patients and these levels were not dependent on the age of individuals. EOMD had a longer duration of the disease (p = 0.004) and a higher prevalence of migraine than LOMD (p = 0.045). CONCLUSIONS: Patients with EOMD have a higher prevalence of migraine than LOMD, but migraine is not associated with any cytokine profile in patients with MD. The levels of CCL18, CCL3, and CXCL4 were different between patients with MD or migraine and controls.
ABSTRACT
Umbilical hernia is a high-prevalence problem in adults. Traditional herniorrhaphy is marked by high recurrence rates, but nowadays, the use of prosthetic materials has improved results and has even brought about lower morbidity rates, making the enterocutaneous fistula an exceptional complication of umbilical hernioplasty. We report on a case of a 54-year-old male who developed a high-debt enterocutaneous fistula 1 year after undergoing an operation for an umbilical hernia by means of a plug-technique hernioplasty. We discuss the case, treatment, and preventable aspects of this complication.
Subject(s)
Hernia, Umbilical/surgery , Intestinal Fistula/surgery , Postoperative Complications/diagnosis , Surgical Mesh , Follow-Up Studies , Hernia, Umbilical/diagnosis , Humans , Intestinal Fistula/diagnosis , Male , Middle Aged , Postoperative Complications/surgery , Risk Assessment , Severity of Illness Index , Time Factors , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
La afectación del hioides por un condrosarcoma es excepcional, habiéndose descrito únicamente 10 casos en la bibliografía. El caso que presentamos se trata de un varón de 24 años que consultó por odinofagia progresiva y masa cervical anterior. La tomografía computarizada mostró una masa de bajo coeficiente de atenuación que dependía del asta izquierda del hioides. Se realizó exéresis de la lesión, siendo catalogada como un condrosarcoma grado II. El paciente permanece asintomático a los 10 años de la intervención (AU)
