Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 4 de 4
Filter
Add more filters










Database
Language
Publication year range
1.
Ann Ig ; 1(3-4): 709-15, 1989.
Article in Italian | MEDLINE | ID: mdl-2483642

ABSTRACT

Neonates born to HBSAg-positive mothers are at increased risk of HBV, mainly because of perinatal exposure. Since 1985 the HBV Regional prevention and control program of Latium recommends prophylaxis both with HBIG and HBV vaccine at birth for all infants born to HBaAg-positive mothers. From 1-1-80 to 1-5-88 89 neonates (52 males, 37 female) from Local Health Units (U.S.L.) FR 2, 3, 4, 5, 6, 7, 8, 9 have been examined at the Centre for Vaccination against HBV of Frosinone. Prophylaxis was accomplished both by HBIG 1 ml. I.M.) at birth and HBV vaccine (5.5 ml. I.M. of HBVAX) at birth, and at 1 and 6 months. All injections were given in the gluteal muscle. Antibody titer to HBsAg (antiHBs) detectable by RIA was tested 1 month after or by the time of the third injection of vaccine. Non-responders (anti HBs less than 10 mUI/ml) were given an extra dose of vaccine (0.5 ml I.M.). 85 neonates accomplished vaccination receiving three injections of HBVAX; 4 neonates received only one dose as their parents refused to continue vaccination. Two neonates (non-responders) out of 85 required another dose of vaccine, but only one seroconvertion appeared. No serious side effects have been seen: one case of anorexia and one case of low-grade fever, with no need to interrupt or modify immunization schedule. In the present study the prophylactic efficacy of HBV vaccine has been demonstrated providing 98.6% of cases with antiHBs titer greater than or equal to 10 mUI/ml, and 84% of cases with antiHBs titer greater than or equal to 150 mUI/ml.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Hepatitis B Antibodies/analysis , Hepatitis B/prevention & control , Viral Hepatitis Vaccines/immunology , Evaluation Studies as Topic , Female , Hepatitis B Vaccines , Humans , Infant, Newborn , Italy , Male , Viral Hepatitis Vaccines/administration & dosage
2.
Ann Ig ; 1(3-4): 761-7, 1989.
Article in Italian | MEDLINE | ID: mdl-2483647

ABSTRACT

In the recent years there is a growing interest in Nosocomial Infections in Italy, because of current studies providing useful information on hospital epidemiology, hospital cost and infection control measures. Besides there is an increasing awareness that clinical and epidemiologic data provide a more important support for infection control program than microbiologic data, which are not always required to identify Nosocomial Infections. Still a reliable microbiology laboratory is an integral support system for infection control program, contributing information on Nosocomial Infection Surveillance and Education of personnel. Over the past five years in the Hospital of Frosinone, prevalence and incidence studies on patient population and microbiologic monitoring were performed. All investigations were accomplished by the Hospital Infection Control Team by collecting and reporting data on special forms, since 1988 information on microbial cultures were included. The prevalence and incidence studies have demonstrated few microbial isolates compared to the number of infections identified. Antibiotic monitoring is considered an integral component of Infection Control Programs, contributing to the surveillance of emerging resistance. All data concerning microbial isolates have been routinely an orderly collected and tabulated. A three-monthly report is distributed throughout the hospital and pertinent data are briefly reviewed. This simple method of surveillance is used to identify trends in problem areas, support antibiotic policy statements and serve as a focus for educational programs of personnel. These routine studies have some limitation: 1) all microbial agents are considered, irrespective of nosocomial infection cases; 2) 100-120 hours of work from an infection control nurse are required. Therefore microbial data are not adequate in containing Nosocomial infections, if not supported by Infection Control Team's investigation.


Subject(s)
Cross Infection/epidemiology , Cohort Studies , Cross Infection/microbiology , Cross-Sectional Studies , Humans , Italy/epidemiology
SELECTION OF CITATIONS
SEARCH DETAIL
...