ABSTRACT
The bodies of the vertebrae are common locations for plasma cell diseases such as multiple myeloma and solitary plasmacytoma. Secondary invasion of the epidural space is infrequent but can cause neurological symptoms. Spinal cord compression due to pure intradural plasma cell infiltration is very rare. The authors report a 25-year-old woman who developed a progressive difficulty in walking due to a solitary spinal dural plasmacytoma. This is the first reported example in the English language literature of a purely intradural spinal plasmacytoma in a patient without other myelomatous lesions. An entirely intradural solitary plasmacytoma has a relatively better prognosis.
Subject(s)
Plasmacytoma/diagnostic imaging , Plasmacytoma/pathology , Spinal Cord Neoplasms/diagnostic imaging , Spinal Cord Neoplasms/pathology , Adult , Female , Humans , Plasmacytoma/surgery , Radiography , Spinal Cord Neoplasms/surgery , Thoracic VertebraeABSTRACT
Multiple and self-inflicted penetrating brain injuries (PBI) rare. PBI are rare. We report the case of multiple self-inflicted PBI in a 45 year old man caused by a nail gun. He was admitted to after shooting four nails into his head and one into his thorax. We review the literature on the topic and describe how this case was successfully managed in our hospital.
Subject(s)
Craniotomy , Foreign Bodies/surgery , Frontal Bone/injuries , Head Injuries, Penetrating/etiology , Temporal Bone/injuries , Antibiotic Prophylaxis , Brain Injuries/diagnostic imaging , Brain Injuries/etiology , Contraindications , Emergencies , Foreign Bodies/diagnostic imaging , Foreign Bodies/etiology , Frontal Bone/surgery , Head Injuries, Penetrating/diagnostic imaging , Humans , Lung/surgery , Lung Injury , Magnetic Resonance Imaging , Male , Middle Aged , Personality Disorders/complications , Pneumothorax/etiology , Pneumothorax/surgery , Premedication , Prognosis , Suicide, Attempted , Temporal Bone/surgery , Thoracic Injuries/etiology , Thoracic Injuries/surgery , Thoracotomy , Tomography, X-Ray ComputedABSTRACT
El linfoma cerebral primario (PCNSL, Primary CNS Lymphoma) es un linfoma no Hodgkin agresivo que se origina en el sistema nervioso central sin evidencia de linfoma en otra localización en el momento del diagnóstico. Los linfomas cerebrales primarios son menos conocidos y caracterizados que sus homólogos los linfomas sistémicos, por tratarse de una entidad poco frecuente hasta hace unas décadas. Sin embargo, el gran ascenso de incidencia que está experimentando esta patología en las últimas tres décadas y que aún no ha sido explicado, hace necesario la existencia de más estudios para conocer mejor la etiopatogenia de esta entidad. Gracias a los nuevos regímenes de tratamiento, el pronóstico de esta patología ha mejorado significativamente en los últimos años. Sin embargo, el tratamiento del linfoma cerebral primario continúa planteando numerosas controversias en la actualidad, debido a su elevada neurotoxicidad en los pacientes mayores de 60 años, grupo de pacientes frecuentemente afectado por esta patología. Para resolver éstas y otras cuestiones se precisa ahondar en el estudio del linfoma cerebral primario y la realización de potentes ensayos clínicos
Primary cerebral lymphoma (Primary CNS Lymphoma, PCNSL) is an aggressive non-Hodgkin lymphoma that originates in the central nervous system without evidence of lymphoma in any other localization at the time of diagnosis. Primary cerebral lymphomas are less well-known and are characterized than their homologues the systemic lymphomas, as they are an entity whose frequency was scarce until a few decades ago. However, the great rise in incidence that this pathology has undergone over the last three decades, and which is still unexplained, makes more studies necessary to better understand the etiopathology of this entity. Thanks to the new systems of treatment, the prognosis of this pathology has improved significantly in recent years. Nonetheless, treatment of primary cerebral lymphoma continues to give rise to numerous controversies at present due to its high neurotoxicity in patients over 60 years of age, a group of patients frequently affected by this pathology. To resolve these and other questions it is necessary to deep in the study of primary cerebral lymphoma and to carry out high quality clinical trials
Subject(s)
Male , Female , Middle Aged , Humans , Lymphoma, Non-Hodgkin/complications , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/therapy , Brain Neoplasms/complications , Brain Neoplasms/diagnosis , Brain Neoplasms/therapy , Hospitals , Lymphoma, AIDS-Related , SpainABSTRACT
Primary cerebral lymphoma (Primary CNS Lymphoma, PCNSL) is an aggressive non-Hodgkin lymphoma that originates in the central nervous system without evidence of lymphoma in any other localization at the time of diagnosis. Primary cerebral lymphomas are less well-known and are characterized than their homologues the systemic lymphomas, as they are an entity whose frequency was scarce until a few decades ago. However, the great rise in incidence that this pathology has undergone over the last three decades, and which is still unexplained, makes more studies necessary to better understand the etiopathology of this entity. Thanks to the new systems of treatment, the prognosis of this pathology has improved significantly in recent years. Nonetheless, treatment of primary cerebral lymphoma continues to give rise to numerous controversies at present due to its high neurotoxicity in patients over 60 years of age, a group of patients frequently affected by this pathology. To resolve these and other questions it is necessary to deep in the study of primary cerebral lymphoma and to carry out high quality clinical trials.
Subject(s)
Brain Neoplasms , Lymphoma, Non-Hodgkin , Brain Neoplasms/complications , Brain Neoplasms/diagnosis , Brain Neoplasms/therapy , Female , Hospitals , Humans , Lymphoma, AIDS-Related , Lymphoma, Non-Hodgkin/complications , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/therapy , Male , Middle Aged , SpainABSTRACT
We describe a previously diagnosed tuberous sclerosis patient that arrived to the hospital with an intracerebral hemorrhage whose origin was an arteriovenous malformation (AVM). A craniectomy was performed and the hematoma was evacuated with the alleviation of the patient. Although the association between tuberous sclerosis and intracerebral hemorrhage is known in the literature it has never been described associated with an AVM.
Subject(s)
Arteriovenous Malformations/complications , Intracranial Hemorrhages/etiology , Tuberous Sclerosis/complications , Arteriovenous Malformations/diagnostic imaging , Arteriovenous Malformations/pathology , Female , Humans , Intracranial Hemorrhages/physiopathology , Middle Aged , Tomography, X-Ray Computed , Tuberous Sclerosis/diagnosisABSTRACT
Describimos el caso de una paciente diagnosticada previamente de esclerosis tuberosa que ingresó de urgencia por una hemorragia intraparenquimatosa debido a una malformación arteriovenosa. La paciente fue intervenida mejorando su sintomatología clínica. A pesar de que la asociación de esclerosis tuberosa y hemorragia intracerebral es conocida en la bibliografía nunca antes se había descrito asociada a una malformación arteriovenosa (AU)
Subject(s)
Middle Aged , Female , Humans , Tomography, X-Ray Computed , Tuberous Sclerosis , Intracranial Hemorrhages , Arteriovenous MalformationsABSTRACT
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