ABSTRACT
OBJECTIVE: The objective of this study was to determine whether puncturing the uterine wall and the amnion causes uterine contractions that result in fetal abnormalities. MATERIALS AND METHODS: An experimental study was performed using four groups of three female rabbits. Group A received a puncture of the amniotic membranes of one of the uteri on day 15 of gestation followed by group B on day 16, group C on day 17, and group D on day 18. The duration and force of contractions and fetal abnormalities were determined. RESULTS: There were immediate contractions after the puncture, which lasted 20 to 132 seconds with forces that ranged from 309 to 4,411 mg. All of the experimental fetuses exhibited anomalies of the head and extremities, exencephaly, cleft palates, and an absence of eye-lids. CONCLUSION: Injury to the uterine wall and the aniion can immediately cause uterine contractions, which are associated with different types of fetal abnormalities.
Subject(s)
Amniotic Band Syndrome/etiology , Pregnancy, Animal , Uterine Contraction/physiology , Uterus/physiopathology , Amniotic Band Syndrome/physiopathology , Animals , Disease Models, Animal , Female , Pregnancy , RabbitsABSTRACT
The case of a 12-year-old boy with the diagnosis of intrahepatic biliary duct cystadenoma is presented. A critical review of the literature revealed less than 100 cases described at present. Differential diagnosis with other intrahepatic cystic lesions of varied etiology is discussed too.
Subject(s)
Adenoma, Bile Duct/diagnosis , Bile Duct Neoplasms/diagnosis , Bile Ducts, Intrahepatic , Cystadenoma/diagnosis , Adenoma, Bile Duct/pathology , Adenoma, Bile Duct/surgery , Bile Duct Neoplasms/pathology , Bile Duct Neoplasms/surgery , Bile Ducts, Intrahepatic/pathology , Bile Ducts, Intrahepatic/surgery , Child , Cystadenoma/pathology , Cystadenoma/surgery , Humans , MaleABSTRACT
Fournier gangrene is a disease which primarily affects adults. This finding makes it rarely seen within the pediatric population. Therefore, we feel it convenient to inform of a case of Fournier gangrene which occurred in an eight day old neonate, successfully treated with surgical debridement, the administering of solutions and antibiotics. This is the youngest patient ever described in the medical literature. Neonate; Fournier; gangrene.
Subject(s)
Fasciitis/pathology , Scrotum , Gangrene , Groin , Humans , Infant, Newborn , MaleABSTRACT
In order to establish a guide for the diagnosis of acute appendicitis, we reviewed the charts of patients with appendectomy. In a 7-year period, 385 patients were studied. The age range was 3 to 15 years. In 53% there was an administration of medications prior to surgery. Perforated appendicitis was found in the majority (53%) of the cases. We could not find any association between age and perforation. Only localized, persistent abdominal pain, peritoneal irritation, anorexia, and vomiting were useful for differential diagnosis. In patients with acute appendicitis (p greater than 0.05), leukocytosis (greater than 10,000/mm3), neutrophilia (greater than 70%) and bands (greater than 3%) were observed in 80% of the cases. The frequency of complications was elevated (39.5%), and the mortality was five times higher than referred in other studies. We propose an algorithm for both opportune diagnosis and treatment of the disease.
