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Acta Haematol ; 146(3): 240-244, 2023.
Article in English | MEDLINE | ID: mdl-36538909

ABSTRACT

The association of glomerulonephritis and malignant hematological disease is uncommon, but well known in chronic leukemias, lymphomas, and monoclonal gammopathies. However, only a few cases of glomerulonephritis and acute myeloid leukemia have been reported in the literature. We describe the first case of a genetically diagnosed acute promyelocytic leukemia presenting with nephrotic range proteinuria that resolved with induction therapy with ATRA and ATO and performed a comprehensive review of the literature.


Subject(s)
Arsenicals , Glomerulonephritis , Leukemia, Promyelocytic, Acute , Humans , Leukemia, Promyelocytic, Acute/complications , Leukemia, Promyelocytic, Acute/diagnosis , Leukemia, Promyelocytic, Acute/drug therapy , Tretinoin/therapeutic use , Induction Chemotherapy , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Glomerulonephritis/diagnosis , Glomerulonephritis/drug therapy , Glomerulonephritis/etiology , Oxides/therapeutic use , Arsenicals/therapeutic use
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