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Dalton Trans ; 52(30): 10286-10293, 2023 Aug 01.
Article in English | MEDLINE | ID: mdl-37466155

ABSTRACT

Human acute monocytic leukaemia cells were tested under both dark and light conditions for their susceptibility to Mn(I) and Ru(II) carbonyl complexes with a diphenyl pyridyl phosphine coligand. The Ru(II) complex (IC50 = 7.13 ± 0.8 µM) displayed higher outstanding potency against leukaemia than the Mn(I) analogue (54.58 ± 4.1 µM) in the dark and both complexes were completely harmless to healthy mouse bone marrow cells.


Subject(s)
Leukemia , Ruthenium , Humans , Animals , Mice , Ruthenium/pharmacology
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