Acute reversible cardiomyopathy and thromboembolism after cisplatin and 5-fluorouracil chemotherapy--a case report.

Acute development of cardiomyopathy and occlusive thromboembolic events following cisplatin and 5-fluorouracil (5-FU) is rare but frequently lethal. The authors report the successful management of such an event in a 52-year-old man with squamous cell carcinoma of the soft palate. The possible pathophysiological mechanisms are discussed.

[Atypical shunting operations in occlusions of the aorta and iliac and femoral arteries]. / Operatsii atipichnogo shuntirovaniia pri okkliuziiakh aorty, pod- vzdoshnykh i bedrennykh arterii.

The results of 110 operations for atypical shunting in occlusions of the aorta and the iliac and femoral arteries are analysed. The authors suggest modifications of operations for transverse femoro-femoral shunting with the use of venous autografts. Shunting of lower limb arteries from the branches of the arch of the aorta made it possible to preserve the limb in 58.8% of patients who otherwise would have to be subjected to amputation. Study of the late-term results shows that atypical reconstructive operations allowed the limb to be preserved by an 8-year follow-up period in 76.1% of patients.

[Transplantation of allogeneic veins and xenogeneic arteries in the reconstructive surgery of occlusive diseases of arteries of the lower extremities]. / Transplantatsiia allogennykh ven i ksenogennykh arterii v rekonstruktivnoi khirurgii okkliuzionnykh porazhenii arterii nizhnikh konechnostei.

The article discusses the results of 91 reconstructive operations with the use of allogeneic veins and xenogeneic arteries in the management of occlusive lesions of the arteries of the lower limbs. The method of obtaining and storing the grafts and the operative techniques are described. Patency of the allogeneic and xenogeneic shunts in occlusions of the lower limb arteries was 47% in the long-term follow-up periods.

[Characteristics of reconstructive surgery in occlusion of the abdominal aorta]. / Osobennosti rekonstruktivnykh operatsii pri okkliuzii briushnoi chasti aorty.

For the 10-year period, 70 patients with occlusion of the abdominal aorta were operated on (10% of the patients operated on for Leriche's syndrome). Severe ischemia of the lower extremities was noted in 25 (35.8%) patients. Low occlusion was diagnosed in 24, middle--in 15, high--in 31 patient. In low and middle occlusion, the end-to-side anastomosis was performed in 17 patients, end-to-end--in 49. In 4 patients, the axillary-femoral shunting was performed. In 32 of 48 cases, the patency of the inferior mesenteric artery was restored. Correction of renal blood flow was performed in 2 patients. Good results were obtained in 92.8% of the cases. The lethality was 7.1%.

[Value of segmental systolic pressure determination in the diagnosis and selection of reconstructive operations of the aorto-ileo-femoral segments]. / Znachenie segmentarnogo sistolicheskogo davleniia dlia diagnostiki i vybora rekonstruktivnykh operatsii v aortopodvzdoshno-bedrennom segmente.

The segmentary systolic pressure along the lower extremities was studied by means of ultrasonic dopplerosphygmomanometry in patients with isolated and associated lesions of the aorto-ileo-femoral segment. The possibility to investigate the hemodynamic significance of stenotic lesions of the arteries is shown which is of value for choice of the method of reconstructive operations in associated lesions of the aorto-ileo-femoral segment.

[Non-invasive methods of examination in the diagnosis of aneurysms]. / Neinvazivnye metody issledovaniia v diagnostike anevrizm.

Radionuclide angiography and ultrasonic echolocation were used for the examination of 38 patients with aneurysms. Isotope angiography was fulfilled in all the 38 patients, ultrasonography was used in 20 patients. Radionuclide angiography and ultrasonography are thought to be sufficiently effective methods of diagnosis of vessel aneurysms.

[Predicting the results of revascularization of the extremities through the deep femoral artery]. / Prognozirovanie rezul'tatov revaskuliarizatsii konechnosti cherez glubokuiu arteriiu bedra.

Immediate results of revascularization of the extremity through the profound femoral artery were compared with data of an analysis of pressure gradients along the extremity. The value of the profound femoral-popliteal collateral index as a method of prognosis of results of profundoplasty was determined. It was found that the index equal to 0.5 or more showed profundoplasty to be not a promising procedure.

[Index of regional systolic pressure--optimal test in the diagnosis of peripheral arterial insufficiency]. / Indeks regionarnogo sistoicheskogo davleniia--optimal'nyi test v diagnostike perifiericheskoi arterial'noi nedostatochnosti.

Dopplerography was used to determine malleolar systolic pressure (MSP) and its derivatives, the brachiomalleolar gradient (BMG) and the melleolar systolic pressure index (MSPI), in 113 patients with chronic arterial insufficiency and varying degrees of ischemia. Thirty normal subjects were taken as controls. The MSPI and the BMG proved to be more informative in differentiating between normal and pathologic conditions, whereas the MSPI and the MSP were more indicative of the limb's viability.