Time delay spectrometry for hydrophone calibrations below 1 MHz.

Knowing the response of miniature ultrasonic hydrophones at frequencies below 1 MHz is important for assessing the accuracy of acoustic pressure pulse measurements in medical ultrasound applications. Therefore, a time delay spectrometry (TDS) system was developed as an efficient means to measure hydrophone sensitivity in this frequency range. In TDS a swept-frequency signal is transmitted. A tracking receiver distinguishes arrivals with different propagation delays by their frequency offset relative to the signal being transmitted, thus eliminating spurious signals such as those reflected from the water surface or tank walls. Two piezoelectric ceramic source transducers were used: a standard planar disk and a disk with varying thickness to broaden the thickness-resonance. This latter design was preferred for its more uniform response without significant sensitivity loss. TDS is not an absolute method, but it was demonstrated to provide efficient, accurate calibrations via comparison with a reference hydrophone using a substitution technique.

Medical ultrasound imager based on time delay spectrometry.

A reflection mode proof-of-concept medical ultrasound imager based on time delay spectrometry has been developed and tested. The system uses a broad band swept-frequency signal operating up to 10 MHz. Signal processing using a fast Fourier transform (FFT) permits extraction of range information. The imager has a higher signal-to-noise ratio than pulse-echo systems which allows high resolution at greater depths. The time delay spectrometry (TDS) spread spectrum operates at lower peak intensities than pulse-echo and permits more control of the spectral content and amplitude of the signal. At present, the system is non-real time which degrades in vivo imaging because of averaging over several cardiac cycles and tissue movement.

Velocity and attenuation of sound in arterial tissues.

The velocity and attenuation of sound has been determined for freshly excised human and canine arterial tissues using a time delay spectrometer (TDS) technique. Frequency was swept from 0 to 10 MHz with data being taken in the range from 2 to 10 MHz. The velocity was determined using a comparison of the time delay for the received signal between a water path and a sample tissue of measured thickness. The velocity of sound was measured for various pathologies and related to biochemical assays of tissue. It was found to increase with increasing ultrasound attenuation of the tissue. The velocity was shown to increase with increased collagen, C, expressed as a percentage of wet weight of the tissue, [V = 17.8* C + 1561 m/s at 37 degrees C, r = 0.77] but was strongly dependent on tissue cholesterol or low levels of calcium. For highly calcified lesions, the velocity of sound was found to be approximately 2000 m/s at 37 degrees C.

Analogue implementation of analytic signal processing for pulse-echo systems.

An alternative to rectification is proposed for detection of an ultrasonic signal. This method is especially useful in medical and non-destructive evaluation (nde) applications. With this method, the magnitude of the complex analytic signal is used to define the envelope of the ultrasonic waveform. The square of this quantity has been shown elsewhere to be equal to the true rate-of-arrival of energy. An earlier study, using digital data processing, has already demonstrated the superior resolvability of closely spaced interfaces obtained with the analytic signal magnitude, as compared to conventional rectification. Here, an analogue implementation is presented which utilizes single-sideband techniques to obtain both quadrature components of the analytic signal and its magnitude. A conventional transducer, pulser, and receiver are used.