[Treatment of allergic rhinitis associated with hypothyroidism].

Fifty five patients with allergic rhinitis and moderate hypothyroidism due to autoimmune thyroiditis have undergone clinical, functional, hormonal, immunological and allergological examinations. Of them, 45 patients received a course of treatment with thyroid hormones and antiallergic drugs while 10 patients received replacement hormonal therapy only. The results of the study demonstrate that treatment of allergic rhinitis associated with hypothyroidism is more effective if antiallergic drugs are added to replacement hormonal therapy.

[Modern characteristics of clinical course and treatment of otogenic purulent meningitis]. / Nekotorye osobennosti klinicheskogo techeniia i lecheniia otogennogo gnoinogo meningita v sovremennykh usloviiakh.

A total of 170 patients aged 2.5 to 60 years have received treatment for otogenic meningitis caused by acute (n=37, 21.2%) or chronic otitis media (n=137, 78.2%). Otogenic meningitis ran atypically with masked clinical manifestations in 32.2% patients. It is thought justified to repeat an antibiotic injection into the cerebrospinal canal in a severe course of meningitis, especially in combination of meningitis with other forms of intracranial complications. If clinical signs of acute otitis media and meningitis manifested weakly and, therefore, otogenic nature of meningitis is questionable, it is recommended to implement an expectant treatment policy. The absence of noticeable positive shifts in the course of the disease after several days of intensive conservative treatment is an indication for surgical intervention.

[Combined pathology of the upper respiratory tract in children with allergic rhinosinusitis and its management]. / Sochetannaia patologiia verkhnikh dykhatel'nykh putei u detei s allergicheskimi rinosinusitami i osobennosti lecheniia.

Concomitant ENT affections were found in all the 172 children aged 4 to 15 years with atopic rhinosinusitis examined by the authors. 44.7% of them were treated surgically, the rest underwent specific immunotherapy. The authors hold that updated immunotropic treatment allows avoiding surgery in more than half of children with atopic rhinosinusitis associated with other disorders of the upper respiratory tract.

[The treatment of atopic rhinitis in children with an accelerated variant of specific immunotherapy]. / Lechenie atopicheskogo rinita u detei uskorennym variantom spetsificheskoi immunoterapii.

An intensified course of specific immunotherapy (36 days) has been tried in 72 children with atopic vasomotor rhinitis. The age of the patients ranged from 5 to 15 years. The effectiveness of the treatment was assessed by nasal mucosa function, cellular and humoral immunity measured throughout the treatment and 6 moths after it. Good results were obtained in 71.1% of the patients, satisfactory in 24.4%, unresponsive children made up 4.2%. No complications occurred. During the treatment adverse reactions were noted in 11 children. Short-term discontinuation of the allergen administration corrected the situation. Clinical, functional and immunological findings permitted the authors to conclude on the expediency of a short-term specific immunotherapy in atopic rhinitis management in children.