ABSTRACT
This is a case of a 71-year-old homosexual man who presented with a 4-day history of fever, weakness and headaches, near syncope, nausea and poor oral intake. The patient denied recent travel or sick contacts but had significant tick bites in the last 4 weeks. A peripheral blood smear showed 0.5% parasitaemia with signet ring appearance organisms consistent with Babesia microti. Serology testing for HIV 1 and 2 by ELISA and western blot were positive. Treatment for Babesia was started and the patient improved. Repeat serology testing for HIV was negative. To the best of our knowledge, this is the first case of false-positive HIV serology that is associated with active babesiosis. In this case, the positive HIV serology turned negative after successful treatment of babesiosis.
Subject(s)
Babesia microti/isolation & purification , Babesiosis/complications , False Positive Reactions , HIV Infections/complications , Tick Bites/complications , Aged , Anti-Bacterial Agents/therapeutic use , Anti-Infective Agents/therapeutic use , Atovaquone/administration & dosage , Atovaquone/therapeutic use , Azithromycin/administration & dosage , Azithromycin/therapeutic use , Babesiosis/blood , Babesiosis/drug therapy , Babesiosis/parasitology , Diagnosis, Differential , Enzyme-Linked Immunosorbent Assay , HIV Infections/blood , HIV Infections/diagnosis , Humans , Male , Serologic Tests/methods , Tick Bites/parasitology , Treatment OutcomeABSTRACT
We present a case of a 74-year-old woman, who was on nitrofurantoin treatment for urinary tract infection (UTI), with fever and chills 7 hours after taking nitrofurantoin. She was hospitalised and evaluated for worsening UTI and sepsis. Initially, it appeared to be secondary to post-UTI sepsis because of possible resistant infection or conditions like pulmonary embolism or acute hepatitis. The patient also developed systemic inflammatory response syndrome, left bundle branch block (LBBB), thrombocytopaenia and transaminitis. Considering the side effects of nitrofurantoin, it was stopped. The patient showed improvement and recovered completely with symptomatic and supportive treatment. During follow-up visits with her primary care physician, thrombocytopaenia, transaminitisandLBBB were found to have been resolved.
Subject(s)
Anti-Infective Agents, Urinary/adverse effects , Bundle-Branch Block/chemically induced , Nitrofurantoin/adverse effects , Systemic Inflammatory Response Syndrome/chemically induced , Aged , Anti-Infective Agents, Urinary/therapeutic use , Female , Humans , Nitrofurantoin/therapeutic use , Urinary Tract Infections/drug therapyABSTRACT
We report a case of septic right superior ophthalmic vein thrombosis complicated by left sphenoid sinusitis with methicillin-sensitive Staphylococcus aureus (MSSA). Early recognition by clinical symptoms, and computed tonography (CT) and magnetic resolution image (MRI) of the head and sinus is needed for prompt surgical drainage of the sinus and appropriate antimicrobial therapy. The use of steroids and anticoagulation for this condition is still debated.
