ABSTRACT
The goal of this study is to provide a benchmark for the use of Monte Carlo simulation when applied to coincidence summing corrections. The examples are based on simple geometries: two types of germanium detectors and four kinds of sources, to mimic eight typical measurement conditions. The coincidence corrective factors are computed for four radionuclides. The exercise input files and calculation results with practical recommendations are made available for new users on a dedicated webpage.
ABSTRACT
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor that is most commonly reported to arise in the subcutaneous tissues of the upper extremities in adolescents and young adults. At present, the WHO classifies this neoplasm as a tumor of uncertain differentiation. AFH is most often clinically regarded as a tumor of intermediate risk due to low reported rates of recurrence and only rare occurrences of metastases. Its histomorphological hallmarks are a prominent lymphoid cuff surrounding a spindle cell neoplasm with syncytial-appearing cytoplasm. Several variant morphologies have been described. Genetically, the tumor is characterized by translocations involving the EWSR1 gene in over 90% of cases. A widening range of anatomical locations and morphological variants of AFH has been reported in the literature; however, neither anatomic location nor specific morphologic features have been shown to correlate with clinical/biological behavior. We report a unique case of AFH arising in the parenchyma of the breast. The neoplasm showed the typical histomorphology including a peripheral lymphoid cuff. The lesional cells in this case were found to be immunoreactive with desmin, and a positive EWSR1 result was confirmed by break-apart fluorescence in situ hybridization testing. To our knowledge, this is the first report of AFH arising in the breast parenchyma of a postmenopausal female.
ABSTRACT
A rare case of giant gastric trichobezoar found in a female patient admitted and treated for chronic gastric disease is presented. The semiological, evolutive and treatment peculiarities in the presented case are discussed.
Subject(s)
Bezoars/diagnosis , Stomach , Adult , Bezoars/pathology , Bezoars/surgery , Chronic Disease , Female , Gastrostomy , HumansABSTRACT
The author presents a case of perforating ulcer of Meckel's diverticulum, with secondary generalized peritonitis in a young patient, admitted and operated for acute appendicitis. The therapy used is described and several semeiologic characteristics of the evolution and treatment of the case presented are discussed.