Impact of Aircraft Delays on Population Noise Exposure in Airport's Surroundings.

The motivation behind this research was to analyse the consequences of aircraft operations' delays on cumulative noise levels produced upon the neighbouring communities and to estimate the relative change in the number of people annoyed by aircraft noise. Many studies showed that residents' reactions to abrupt changes in noise exposure were more intense compared to the anticipated ones. Aircraft delays may cause such abrupt changes in noise exposure by increasing the traffic in some periods compared to the scheduled traffic. The methodology applied includes noise contour development for two different scenarios for intervals where aircraft delays occur. Only delays connected with the Total Airport Management (TAM) were analysed, since such delays can be influenced by airports. The first scenario considered the influence of aircraft operations on population noise exposure without TAM delays, whereas the second one included all delayed flights (actual traffic). The proposed method was tested through case studies of three southeast European airports. The results showed that the highest potential of decrease in the number of people annoyed by the noise was recorded at Nis Airport (59%), followed by Zadar Airport (49%) and Sarajevo Airport (25%). Similar results were obtained in the context of highly annoyed people.

Comparative UAV Noise-Impact Assessments through Survey and Noise Measurements.

Possibilities to use unmanned aerial vehicles (UAVs) are rapidly growing. With the development of battery technologies, communication, navigation, surveillance, and autonomous systems in general, many UAVs are expected to operate at relatively low altitudes. Thus, the problem of UAV noise impact on human health and well-being will be more pronounced. In this paper, we conducted noise measurements of two UAVs of different performance (quadrotor and hexarotor) in flying up and down, hovering, and overflight procedures. Respondents of good hearing who were confirmed by audiogram measurement and had participated in the survey during UAV noise measurement gave their subjective assessments on the UAV noise perception. UAV noise measurements and subjective respondents' assessments were analysed and related. UAV noise analysis showed that the parameters measured at the same measurement point for the hexarotor were higher than those for the quadrotor in flying up and down and flying-over procedures. Low frequency noise was present in the noise spectrum of both drones. Participants were able to distinguish between the noise of UAVs and had a generally more negative experience with the hexarotor. Regardless of the noise perception, more than 80% of the respondents believe there are more pros than cons for UAV introduction into everyday life.

Mathematical models for absorption and efficacy of ovarian cancer treatments.

The creation of personal and individualized anti-cancer treatments has been a major goal in the progression of cancer discovery as evident by the continuous research efforts in genetics and population based PK/PD studies. In this paper we use our clinical decision support tool, called ChemoDSS, to evaluate the effectiveness of three treatments recommended by the NCCN guidelines for ovarian cancer using pre-clinical data from the literature. In particular, we analyze the treatments of PC (i.e., Paclitaxel and Cispaltin), DC (i.e., Docetaxel and Carboplatin), and PBC (i.e., Paclitaxel, Bevacizumab, and Carboplatin). Our in silico analysis of the ovarian cancer treatments shows that PC was the most effective regimen for treating ovarian cancer compared to DC and PBC, which is consistent with literature findings. We demonstrate that we can successfully evaluate the effectiveness of the selected ovarian cancer treatment regimens using ChemoDSS.