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1.
Zhong Nan Da Xue Xue Bao Yi Xue Ban ; 41(9): 975-8, 2016 Sep 28.
Article in Chinese | MEDLINE | ID: mdl-27640797

ABSTRACT

OBJECTIVE: To investigate the clinical efficacy of oral medicine and sodium hyaluronate in prevention of intrauterine adhesions after artificial abortion.
 METHODS: A total of 572 patients with early pregnancy termination through artificial abortion, who experienced two or more times of abortion, were retrospectively analyzed. Patients were randomly and voluntarily divided into 4 groups: an artificial cycle group, a drospirenone and ethinylestradiol tablets group, a sodium hyaluronate group, and a control group. The thickness of the endometrium, return time of menses, and the status of intrauterine adhesions were observed.
 RESULTS: The thickness of the endometrium in the artificial period group was greater than that in the control group (P<0.001). It was less in the drospirenone and ethinylestradiol tablets group comparing with that in the control group (P<0.001). There was no significant difference in the thickness of the endometrium between the sodium hyaluronate group and the control group (P=0.717). Return time of menses in the artificial menstrual cycle group and the drospirenone and ethinylestradiol tablets group was shorter than that in the control group (P<0.001). There was no significant difference in return time of menses between the sodium hyaluronate group and the control group (P=0.813). The incidence of intrauterine adhesions could be reduced by the 3 preventive measures (All P<0.01).
 CONCLUSION: Drugs for artificial cycle and drospirenone and ethinylestradiol tablets medication immediately after artificial abortion can effectively promote endometrial repair and reduce the incidence of intrauterine adhesions. However, for the patients with poor compliance, drospirenoneand ethinylestradiol tablets are the first choice for prevention of intrauterine adhesion.


Subject(s)
Abortion, Induced/adverse effects , Androstenes/therapeutic use , Ethinyl Estradiol/therapeutic use , Hyaluronic Acid/therapeutic use , Tissue Adhesions/prevention & control , Androstenes/pharmacology , Endometrium/anatomy & histology , Endometrium/drug effects , Ethinyl Estradiol/pharmacology , Female , Humans , Hyaluronic Acid/pharmacology , Menstrual Cycle/drug effects , Menstruation/drug effects , Pregnancy , Tissue Adhesions/etiology
2.
Zhong Nan Da Xue Xue Bao Yi Xue Ban ; 40(11): 1229-33, 2015 Nov.
Article in Chinese | MEDLINE | ID: mdl-26643427

ABSTRACT

OBJECTIVE: To investigate the risky factors for pelvic floor functional disorder.
 METHODS: A total of 346 patients, who undergone surgery for pelvic floor reconstruction from January 2007 to December 2013 in the Third Affiliated Hospital of Zhengzhou University, were enrolled for this study and served as an experimental group. Meanwhile, 349 female healthy subjects were selected as a control group. The data including the times of gestation and parity, history of menopause, hysterectomy surgery, uterine fibroid and leucorrhea were recorded.
 RESULTS: Compared with the controls, the numbers of people with hysterectomy, menopause and clean vagina≥III degree, lack of lactobacillus as well as the times of gestation and parity in the experimental group were significantly increased (P<0.05). The history of hysterectomy, the times of gestation and parity and lack of lactobacillus in vagina were the independent risk factors of pelvic floor dysfunction.
 CONCLUSION: The history of hysterectomy, the times of gestation and parity, and clean vagina may involve in the occurrence and development of pelvic floor functional disorder, and the existence of lactobacillus in the vagina might be a protective factor.


Subject(s)
Pelvic Floor Disorders/physiopathology , Pelvic Floor/physiopathology , Case-Control Studies , Female , Humans , Hysterectomy , Lactobacillus/isolation & purification , Menopause , Multivariate Analysis , Parity , Pregnancy , Risk Factors , Vagina/microbiology
3.
Microb Ecol ; 69(1): 45-58, 2015 Jan.
Article in English | MEDLINE | ID: mdl-25204749

ABSTRACT

Tribological mechanism of the diatom frustule with multi-layers of pores is studied with the liquid-solid interaction (FSI) method. Based on the reconstructed representative Coscinodiscus sp. frustule with two-layer porous structure, the tribological performances for the diatom frustule at its different pore diameter ratios, pore depth ratios, and velocities are solved through governing equations involved with FSI method. The numerical result shows that the existence of the two-layer porous structure of the diatom helps to reduce the friction between it and ambient water, and to increase its ability to resist the ambient water pressure. The two-layer porous structure effectively improve the tribological performances for the diatom frustule due to the change in the frustule velocity.


Subject(s)
Diatoms/cytology , Diatoms/metabolism , Porosity
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