[Sensitivity of Shigella to antibiotics]. / O chuvstvitel'nosti shigell k antibiotikam.

Three hundred and twenty two Shigella cultures isolated from dysentery patients within 1986-1989 were tested with the use of standard paper disks for their sensitivity to levomycetin, streptomycin, tetracycline, monomycin, neomycin, kanamycin, erythromycin, gentamicin, carbenicillin, ampicillin, oxacillin, methicillin and doxycycline. The number of the cultures belonging to Shigella sonnei amounted to 85.1 per cent of the total number of the strains studied. 91.9, 89.5, 87.3, 87.3, 80.1 and 80.1 per cent of the cultures were sensitive to gentamicin, kanamycin, carbenicillin, neomycin, levomycetin and ampicillin, respectively. 99.4 per cent of the isolates were resistant to streptomycin and 97.2 per cent were resistant to tetracycline. The sensitivity to erythromycin remained rather high (70.2 per cent). The overwhelming majority of the Shigella sonnei isolates had multiple resistance.

[Antibiotic sensitivity of Shigella isolated from patients from 1974-1985]. / Chuvstvitel'nost' k antibiotikam shigell, vydelennykh ot bol'nykh v 1974-1985 gg.

Antibiotic sensitivity of 3524 Shigella cultures isolated from patients in 1974-1982 and 414 cultures isolated in 1983-1985 was assayed with standard paper disks. The isolates of 1974-1982 were mostly responsive to ampicillin, carbenicillin, kanamycin, gentamicin, monomycin, neomycin and chloramphenicol. Certain differences in the level of the antibiotic resistance were observed in the Shigella isolates belonging to diverse species. Polyresistant cultures of Shigella amounted to 96.5% and ranged from 88.5 to 99.4% in different years. The number of the cultures with multiple resistance among Shigella sonnei was somewhat higher than that among the Flexneri and Newcastle bacilli. The Shigella isolates of 1983-1985 were mostly responsive to gentamicin, carbenicillin, neomycin, kanamycin and monomycin. 55.5% of the Shigella isolates were responsive to chloramphenicol and only 3.1% to tetracycline. Almost all the causative agents of dysentery isolated within that period were polyresistant. Phenotypic characteristics of multiple resistance in the Shigella cultures were studied.

[Salmonellal sensitivity to antibiotics in 1975-1979 and its characteristics in S. typhimurium]. / Chuvstvitelk'nost' sal'monell k antibiotikam za 1975-1979 gg. i osoebnnosti ee u S. typhimurium.

Sensitivity of 314 Salmonella strains of 16 serotypes of the main groups ABCDE isolated from patients with salmonellosis in 1975-1979 was studied with the method of standard paper disks with respect to levomycetin, streptomycin, tetracycline, monomycin, erythromycin, oleandomycin and in a part of the cultures to kanamycin, ristomycin, ampicillin, carbenicillin and polymyxin. 78 per cent of the strains fell within S. typhimurium. It was found that S. typhimurium had higher resistance levels to the above antibiotics and the so called "hospital" strains of the pathogens were mainly resistant simultaneously to 4-12 antibiotics. The Salmonella strains of the other serotypes isolated mainly in 1975-1977 preserved sufficient sensitivity to the antibiotics used for the most prolonged periods and most widely in therapy.

[Antibiotic sensitivity of the Salmonella isolated from humans ill with salmonellosis in 1967-1974]. / Chuvstvitel'nost' sal'monell k antibiotikam, vydelennykh ot bol'nykh sal'monellezami liudei za 1967-1974 gg

Sensitivity to levomycetin, streptomycin, chlortetracycline, oxtetracycline, tetracycline, neomycin, monomycin and erythromycin of 548 fresh isolates of Salmonella of 32 serotypes of the main groups A, B, C, D and E was studied. The cultures were isolated from salmonellosis patients within 1967-1974. Sensitivity to neomycin, monomycin, levomycetin and streptomycin was found respectively in 96.9, 91.1, 76.5 and 74.8 per cent of the cultures. High sensitivity of the cultures was observed only to levomycetin (15.1 per cent). With respect to tetracyclines the isolates were mainly resistant (24.2-47.2 per cent) or low sensitive (25-26.5 per cent). 70.3 per cent of the strains were resistant to erythromycin and 24.1 per cent were of low sensitivity. The causative agents of typhoid fever, paratyphoid fever A and B were more sensitive to levomycetin and tetracycline as compared to other Salmonella. A polyvalent Salmonella bacteriophage lyzed from 94.2 to 100 per cent of the Salmonella cultures tested.

[Observations on the sensitivity to antibiotics of the Shigella isolated from patients in 1966-1973]. / Nabliudeniia za chuvstvitel'nos'iu k antibiotikam shigell, vydelennykh ot bol'nykh v 1966-1973 gg

Sensitivity to levomycetin, streptomycin, chlortetracycline, oxytetracycline, monomycin, neomycin and erythromycin of 3766 strains of Shigella isolated from dysentery patients within 1966-1973 was determined with the method of standard discs. The strains proved to be resistant to tetracycline (94.3-99.4 per cent), streptomycin (85.1-94.9 per cent) and levomycetin (69-93.1 percent). By present the dysentery bacilli have preserved their sensitivity to monomycin (88.2 per cent) and neomycin (98.2 per cent). Cultures insensitive or slightly sensitive to erythromycin predominated. Strains with multiple resistance amounted to 79 per cent, including 82.5 per cent of Shigella Sonne, 51.8 per cent of Shigella Flexneri and 35.9 percent of Newcastle bacteria.