ABSTRACT
A follow-up study of 15 (15-17) years of 320 consecutive Zweymuller total hip arthroplasties is presented. Age at surgery was 67 (29-99) years. A total of 164 (51.3%) patients had died. Clinical and radiological examinations were available for 97 (30.3%), phone interviews and radiological examinations for 4 (1.3%) hips, and phone follow-ups for 49 (15.3%). There were 6 (1.9%) patients who were lost to follow-up. The Harris Hip Score results in a median value of 88. According to the Kaplan-Meier method, a survival rate of the cup/inlay of 98% (95% confidence interval, 95%-99%) after 17 years was achieved. For the stem/head, the survival rate was 98% (95% confidence interval, 94%-99%). In 95.2% of patients, no operative revision was required. The rate of aseptic loosening was 2% for the acetabular and 1% for the femoral component.
Subject(s)
Arthroplasty, Replacement, Hip/instrumentation , Hip Prosthesis , Osteoarthritis, Hip/surgery , Adult , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/methods , Female , Follow-Up Studies , Hip Joint/diagnostic imaging , Hip Joint/physiology , Hip Joint/surgery , Humans , Longitudinal Studies , Male , Middle Aged , Prosthesis Failure , Radiography , Treatment OutcomeABSTRACT
Bence Jones (free light chain-FLC) proteinuria is usually detected by immunofixation electrophoresis (IFE) of urine. With a new, automated immunoassay, it is now possible to quantify FLC in serum and urine. In the present study, we compared different routine methods for monoclonal FLC screening. From our results we conclude that the measurement of FLC in serum is highly sensitive and should replace urine tests. Additionally, possible kidney dysfunction, caused by nephrotoxicity of FLC, should be assessed by urine protein analysis and cystatin C measurements.
