[Study of the effect of rations containing dietary fiber on the level of total lipids and cholesterol in the blood and liver of the rat during a 6.5-month experiment]. / Izuchenie vliianiia ratsionov, soderzhashchikh pishchevye volokna, na uroven' obshchikh lipidov i kholesterina krovi i pecheni krys v usloviiakh 6.5-mesiachnogo éksperimenta.

The influence of the following food fibers: wheat bran, citrus pectin, microcrystallized cellulose, methyl cellulose, was studied in experiments on male Wistar rats. Basing on the data obtained it has been suggested that the diets with pectin are conducive to secretion of general lipids and sterols from the liver. Comparison of the action of natural food fibers (wheat bran, pectin) with artificial fibers (microcrystallized cellulose, methyl cellulose) has not revealed any changes in the blood cholesterol level. At the same time a lower content of total lipids and cholesterol was recorded in the liver of rats that had received pectin and bran.

[Effect of the ratio of polyunsaturated fatty acids of the omega 6 and omega 3 families in the diet of rats on the cholesterol content of the blood plasma and liver]. / Vliianie sootnosheniia polinenasyshchennykh zhirnykh kislot semeistv omega 6 i omega 3 v ratsione krys na soderzhanie kholesterina v plazme krovi i pecheni.

The influence of polyunsaturated fatty acids omega 6 and omega 3 on the cholesterol level in the blood plasma and liver was studied in rats fed with rations containing no fats during 6 weeks. The total cholesterol content in the blood plasma decreased in the animals given ration with eicosapentaenoic acid (EPA), and the ration containing "Iwashi" sardine fat combined with sunflower oil. In the animals receiving the latter ration the level of free cholesterol in the liver lowered, however, the level of total cholesterol and its esters rose that could be explained by the reduction of the ratio of fatty acids 20:4/18:2 in cholesterol esters.

[Hypocholesterolemic action of oils from the seeds of new selection varieties of winter rape and winter cress in trials on rats]. / Izuchenie gipokholesterinemicheskogo deistviia masel iz semian novykh selektsionneykh sortov rapsa i surepitsy v opytakh na krysakh.

The capacity of new selected sorts of rape and winter cress oils to decrease a high cholesterol level in the blood and liver was studied in "cholesterol" rats. Basing on the data obtained a conclusion could be made on the hypocholesterolemic effect of the oils when they were given to animals. It is suggested that rape oil ("Agat", "Kubanskoye") and winter cress oil ("Sibiryachka") initiate the lipid transport in the blood and tissues thus leading to the reduction of the cholesterol level in the blood and liver tissue in "cholesterol" rats.

[Changes in the sterol content of soybean oil after its thermal processing]. / Izmenenie sostava sterolov soevogo masla posle ee termicheskoi obrabotki.

A study was made of alterations in the composition of soybean oil sterols after thermal treatment. It was established that in heat-exposed oils, the content of total sterols dropped 20 to 50%. Analysis of a sample of free sterols from soybean oil heated for 13 h demonstrated a slight decrease in the content of stigmast-5-en-3 beta-ol at the expense of a rise in the concentration of delta 5-avenasterol, citrostadienol, and 24-methylene cycloartanol.

[Accumulation and transformation of dietary ergosterol in rats]. / Izuchenie nakopleniia i transformatsii érgosterina v organizme krysy pri alimentarnoi ego nagruzke.

The results of experiments on rats given the ergosterol-containing diet for a long time indicate that ergosterol was incorporated in liver tissues in trace amounts which are not comparable with ergosterol concentrations exerting an effect in model experiments. Ergosterol was not detected in the liver after 3-day experiments. At the same time it was established that the proportion of unchanged ergosterol in rat feces was about 16% of the amount administered per os. The products of a possible ergosterol transformation (dehydroneoergosterol-24-methyl-1,3,5 (10), 6,8 (9), 22-hexaen-3 beta-ol; 24-methylcholesta-7,24 (28)-dien-3 beta-ol; 4-cholesta-7,22,25 (?)-trien-3 beta-ol; 4-methylcholesta-7,22 (?)-dien-3 beta-ol, and so forth were identified in feces.