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1.
Pediatr. aten. prim ; 21(82): e61-e66, abr.-jun. 2019. graf
Article in Spanish | IBECS | ID: ibc-184587

ABSTRACT

Objetivo: describir la tuberculosis infantil de 2005 a 2015 en Navarra, con datos demográficos, clínicos, radiológicos, microbiológicos, tratamiento y evolución. Material y métodos: estudio descriptivo retrospectivo a partir de datos de historia clínica de los pacientes atendidos entre 2005 y 2015. Resultados: 52 pacientes, 57,7% varones, 42,3% mujeres, mediana de edad cuatro años, 38,5% inmigrantes, 61,5% hijos de inmigrantes. Distribución homogénea en los diez años, excepto un brote en 2011. Sintomáticos el 69,2%. En el 63,5% de los pacientes el caso índice es conocido. La forma clínica más frecuente es la pulmonar (82,7%). La radiología fue patológica en el 86,5%, se realizó tomografía computarizada pulmonar en el 82,7% (95,3% patológicos). El 71,2% de los cultivos fueron positivos para Mycobacterium tuberculosis (sensibles 92,3%). Tratamiento con cuatro fármacos y posteriormente dos de 6 a 12 meses. Evolución: 84,6% curación, 13,5% secuelas y un exitus. Conclusiones: la tuberculosis es un problema de salud infantil cuya forma más frecuente es pulmonar. Evoluciona favorablemente, pero presenta morbimortalidad. Es imprescindible tenerla en cuenta para diagnóstico y tratamiento precoz


Objective: to describe tuberculosis in Pediatrics from 2005-2015 in Navarra, attending to demographic, clinic, radiologic, microbiologic, treatment and evolution data. Material and methods: a retrospective descriptive study based on data from the clinical history of patients treated between 2005 and 2015. Results: we studied 52 patients, 57.7% men, 42.3% women, age: 4 years old. 38.5% are immigrant and 61.5% children from immigrants. During the last 10 years, the distribution has been homogeneous, despite of one outbreak in 2011. 69.2% had symptoms when diagnosed. In 63.5% we knew index case. The most frequent clinical form is the pulmonary one. Simple Rx was pathological in 86,5% of cases and CT was applied in 82,7% (being diagnostic in 95'3% of them). 71,2% of microbiological cultures were positive for Mycobacterium tuberculosis (92,3% of them were sensible to M. tuberculosis sensible to standard treatment). All patients were treated with four drugs and then two up to 6-12 months. Follow up: 84.6% healed, 13.5% healed but there were sequelae and one of our patients died. Conclusion: tuberculosis represents a problem in children health. Pulmonary tuberculosis is the most frequent clinical form. Normally, it evolves favourably but morbimortality exists. It is essential to consider tuberculosis in order to have an early diagnosis and treatment


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Tuberculosis/epidemiology , Mycobacterium tuberculosis/isolation & purification , Mycobacterium tuberculosis/pathogenicity , Tuberculosis/prevention & control , Tuberculin Test/methods , Antitubercular Agents/therapeutic use
2.
Pediatr. aten. prim ; 18(70): 175-177, abr.-jun. 2016. ilus
Article in Spanish | IBECS | ID: ibc-153807

ABSTRACT

La afectación ganglionar por Mycobacterium tuberculosis puede ocurrir tras una diseminación linfohemática a partir de una afectación primaria pulmonar, o por primoinfección extrapulmonar, cuya puerta de entrada son las mucosas o contacto con objetos contaminados. Se presenta el caso de un niño de diez años, nacido en España, afecto de adenitis tuberculosa en la región inguinal, cuya infección se produjo tras una herida en el pie ocurrida en una playa de Brasil. Tras el inicio de la terapia antituberculosa desarrolló una escrófula que requirió desbridamiento quirúrgico, con buena evolución posterior (AU)


Tuberculous lymphadenitis can be caused either by an haematogenous spread from a pulmonary primary form or by an extrapulmonary infection due to cutaneous lesions or contact with contaminated items. We present a 10-year-old spanish boy, who has an inguinal tuberculous lymphadenitis. Infection was secondary to a foot injury caused in a Brazilian beach. A scrofula appeared after triple therapy was instaured, needing surgical debridement with a favourable clinical evolution (AU)


Subject(s)
Humans , Male , Child , Lymphadenitis/complications , Lymphadenitis/drug therapy , Lymphadenitis/pathology , Mycobacterium tuberculosis , Mycobacterium tuberculosis/isolation & purification , Polymerase Chain Reaction/methods , Polymerase Chain Reaction/standards , Polymerase Chain Reaction , Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Early Diagnosis , Antibiotics, Antitubercular/therapeutic use , Antitubercular Agents/therapeutic use , Tuberculin/analysis , Biopsy, Fine-Needle/instrumentation , Biopsy, Fine-Needle/methods , Tuberculosis, Lymph Node/complications , Tuberculosis, Lymph Node/drug therapy
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