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2.
Rev. esp. patol. torac ; 25(2): 139-142, abr.-jun. 2013. ilus
Article in Spanish | IBECS | ID: ibc-114507

ABSTRACT

Las calcificaciones metastásicas pulmonares son un proceso poco frecuente, que se asocian a una gran variedad de entidades clínicas. Es una enfermedad inicialmente asintomática, pero puede conducir al fallo respiratorio grave y fulminante. Los depósitos de calcio en el parénquima pulmonar suelen localizarse con mayor frecuencia en lóbulos superiores, pudiendo ser la distribución de las lesiones unilateral o bilateral. La radiografía de tórax puede ser normal, aunque entre sus alteraciones radiológicas, destacan la presencia de nódulos o calcificaciones. Presentamos el caso de una mujer de 50 años con antecedentes personales de insuficiencia renal crónica terminal en tratamiento con hemodiálisis desde hacía 2 meses, que comenzó con febrícula y disnea a moderados esfuerzos, presentando en la radiografía de tórax un infiltrado alveolar bilateral (AU)


Overview: Lung metastatic calcifications are a rare process, that are associated with a wide variety of clinical entities. It is initially asymptomatic disease, but it can lead to serious and fulminant respiratory failure. The calcium deposits in the lung parenchyma are often located more often in upper lobes, and may be unilateral or bilateral. Chest x-ray may be normal, although between their radiological alterations, highlights the presence of nodules or calcifications. We present the case of a woman of 50 years with a personal history of terminal chronic renal failure treated with hemodialysis for 2 months, it started with low grade fever and shortness of breath to moderate efforts, presenting bilateral alveolar infiltration on chest x-ray (AU)


Subject(s)
Humans , Female , Middle Aged , Calcinosis/physiopathology , Renal Insufficiency, Chronic/complications , Renal Dialysis , Hyperparathyroidism, Secondary/complications , Dyspnea/etiology , Radiography, Thoracic
3.
An. pediatr. (2003, Ed. impr.) ; 77(1): 5-11, jul. 2012. ilus, tab
Article in Spanish | IBECS | ID: ibc-101253

ABSTRACT

Objetivo: Estudiar la utilidad de una modalidad específica de fisioterapia respiratoria, consistente en maniobras de espiración lenta prolongada seguida de tos provocada, en el tratamiento de la bronquiolitis aguda (BA) del lactante hospitalizado. Pacientes y métodos: Ensayo clínico aleatorizado y doble ciego realizado con 236 pacientes de edad inferior a 7 meses e ingresados con diagnóstico de bronquiolitis aguda, primer episodio, en la sección de lactantes de un hospital pediátrico de Madrid. Los pacientes fueron distribuidos aleatoriamente en el momento del ingreso en dos grupos: los que recibieron maniobras de fisioterapia respiratoria y los que recibieron otras maniobras placebo. Únicamente los fisioterapeutas que intervinieron en el estudio conocían la asignación de los niños. Los días de hospitalización y las horas de oxigenoterapia fueron utilizados como medida de resultado. Resultados: De la totalidad de los niños estudiados, el 57,6% recibió maniobras de fisioterapia respiratoria y el 42,4% restante recibió maniobras placebo. En el grupo que recibió fisioterapia la estancia media en el hospital fue de 4,56 días (intervalo de confianza [IC] del 95%, 4,36-6,06) y el tiempo medio de oxigenoterapia fue de 49,98 horas (IC del 95%, 43,64-67,13) frente a 4,54 días (IC del 95%, 3,81-5,73) y 53,53 horas (IC del 95%, 48,03-81,40), respectivamente, en el grupo que no recibió fisioterapia. Estos resultados en ningún caso alcanzan significación estadística. Los pacientes con estudio positivo de VRS (virus respiratorio sincitial) en aspirado nasofaríngeo y que recibieron maniobras de fisioterapia necesitaron menos horas de oxigenoterapia 48,80 horas (IC del 95%, 42,94-55,29) frente a 58,68 horas (IC del 95%, 55,46-65,52), respectivamente, siendo el único resultado estadísticamente significativo (p=0,042). Conclusiones: Los resultados obtenidos muestran que la fisioterapia respiratoria no ha sido eficaz para reducir la estancia hospitalaria ni el tiempo de oxigenoterapia en los pacientes con bronquiolitis aguda, sin embargo, en los niños con estudio positivo de VRS en aspirado nasofaríngeo se observó una necesidad menor de horas de oxígeno (p=0,042) (AU)


Objetive: To study the utility of chest physiotherapy by increased exhalation technique with assisted cough in the acute bronchiolite of the hospitalized new-born babys. Patients and methods: Double-blind clinical trial accomplished on 236 patients of age lower than 7 months and hospitalizad with diagnosis of acute bronchiolitis, first episode, in a pediatric department in Madrid. The patients were randomized in two groups: those who have received maneuvers of chest physiotherapy and those who have received maneuvers placebo. Only physiotherapist were aware of the allocation group of the infants. The days of hospitalization and the hours of oxygen therapy were used like result measurement. Results: From the totality of the studied children 57,6% received maneuvers of chest physiotherapy and 42,4% remaining received maneuvers placebo. In the group that received chest physiotherapy the average stay in the hospital was 4,56 days (95% confidence interval [CI] 4,36-6,06) and the average time of oxygen therapy was 49,98 (95% CI 43,64-67,13) hours opposite to 4,54 days (95%CI 3,81-5,73) and 53,53hours (95% CI 48,03-81,40) respectively in the group that did not receive chest physiotherapy. In the patients with analytical print for VRS and that received chest physiotherapy less hours of oxygen therapy were needed 48,80hours (95% CI 42,94-55,29) opposite to 56,68hours (95% CI 55,46-65,52) respectively, being the only one turned out as per statistics significantly (P=.042). Conclusions: Results show that chest physiotherapy has not been effective in reducing hospital stay or length of oxygen therapy in patients with acute bronchiolitis, but in the positive study of children with respiratory syncytial virus in nasopharyngeal aspirate showed a reduced need hours of oxygen. hours (P=.042)(AU)


Subject(s)
Humans , Male , Female , Infant , Bronchiolitis/therapy , Breathing Exercises , Child, Hospitalized , Double-Blind Method , Evaluation of the Efficacy-Effectiveness of Interventions
4.
An Pediatr (Barc) ; 77(1): 5-11, 2012 Jul.
Article in Spanish | MEDLINE | ID: mdl-22281403

ABSTRACT

OBJECTIVE: [corrected] To study the utility of chest physiotherapy by increased exhalation technique with assisted cough in the acute bronchiolite of the hospitalized new-born babys. PATIENTS AND METHODS: Double-blind clinical trial accomplished on 236 patients of age lower than 7 months and hospitalizad with diagnosis of acute bronchiolitis, first episode, in a pediatric department in Madrid.The patients were randomized in two groups: those who have received maneuvers of chest physiotherapy and those who have received maneuvers placebo. Only physiotherapist were aware of the allocation group of the infants. The days of hospitalization and the hours of oxygentherapy were used like result measurement. RESULTS: From the totality of the studied children 57,6% received maneuvers of chest physiotherapy and 42,4% remaining received maneuvers placebo. In the group that received chest physiotherapy the average stay in the hospital was 4,56 days (95% confidence interval [CI] 4,36-6,06) and the average time of oxygentherapy was 49,98 (95% CI 43,64-67,13) hours opposite to 4,54 days (95%CI 3,81-5,73) and 53,53 hours (95% CI 48,03-81,40) respectively in the group that did not receive chest physiotherapy. In the patients with analytical print for VRS and that received chest physiotherapy less hours of oxygen therapy were needed 48,80 hours (95% CI 42,94-55,29) opposite to 56,68 hours (95% CI 55,46-65,52) respectively, being the only one turned out as per statistics significantly (P=.042). CONCLUSIONS: Results show that chest physiotherapy has not been effective in reducing hospital stay or length of oxygentherapy in patients with acute bronchiolitis, but in the positive study of children with respiratory syncytial virus in nasopharyngeal aspirate showed a reduced need hours of oxygen. hours (P=.042).


Subject(s)
Bronchiolitis/therapy , Respiratory Therapy/methods , Double-Blind Method , Female , Humans , Infant , Infant, Newborn , Male
5.
Rev. patol. respir ; 14(3): 97-99, jul.-sept. 2011. ilus
Article in Spanish | IBECS | ID: ibc-101896

ABSTRACT

La administración intravesical del bacilo de Calmette-Guérin (BCG) puede producir complicaciones infecciosas locales y sistémicas. Las complicaciones sistémicas son infrecuentes, aunque muy graves. Presentamos el caso de un varón con dicho tratamiento que comienza con fiebre e inicialmente se atribuye a una sepsis urológica. Posteriormente se sospecha una diseminación hematógena y una neumonitis que se diagnostica por una gammagrafía con galio-67. Además, se aísla en orina Mycobacterium bovis (AU)


Intravesical administration of Bacille Calmette-Guérin (BCG) may cause local and systemic infectious complications. Systemic complications are rare but very serious. We report the case of a man with such treatment who began with fever what was initially attributed to a urological sepsis. After, hematogenous dissemination and pneumonitis were suspected, these being diagnosed by gallium-67 scintigraphy. In addition, Mycobacterium bovis was isolated in the urine (AU)


Subject(s)
Humans , Mycobacterium bovis/pathogenicity , BCG Vaccine/adverse effects , Pneumonia/etiology , Administration, Intravesical , Urinary Bladder Neoplasms/drug therapy
6.
Rev. esp. pediatr. (Ed. impr.) ; 64(6): 438-440, nov.-dic. 2008. tab
Article in Spanish | IBECS | ID: ibc-60236

ABSTRACT

Introducción: Se ha señalado que las infecciones del tracto urinario (ITU) por gérmenes diferentes a E. Coli se asocian con mas frecuencia a malformaciones vesicoureterales y cicatrices renales. El objetivo de este estudio es analizar las características analíticas y las pruebas de imagen (ECO y CUMS) en lactantes ingresados con el diagnóstico de primera ITU y evaluar si hay diferencias entre aquellas producidas por E. coli y las producidas por otros patógenos. Sujetos y métodos: Estudio retrospectivo en 203 pacientes diagnosticados de primera ITU ingresados en el Servicio de Lactantes de nuestro Hospital entre los años 2003 y 2007. Se recogieron datos de laboratorio al ingreso y se les realizó pruebas de imagen (ECO y CUIMS), junto con un seguimiento posterior en Consultas Externas. Resultados: De los 203 niños incluidos, 174 (85,7%) resultaron positivos para E. coli y 29 (14,3%) para diferentes patógenos no E. coli. Estos últimos presentaron más alteraciones en la ECO que los no E. coli: OR =2,61 (1,12-6,05). Asimismo, presentaron mayor frecuencia de anomalías nefrourológicas, considerando como tal la presencia de alteraciones en la ECO y/o CUMS: OR=4,57 (2,01-10,4). También comprobamos que pacientes cuyos urocultivos fueron positivos para patógenos diferentes a E. coli mostraron más frecuentemente reflujo vesicoureteral grado ≥3 que los E. coli: OR = 7,9 (2,68-27,2), p<0,05. En nuestro estudio no hemos encontrado diferencias en el resto de parámetros analizados (datos epidemiológicos y de laboratorio). Conclusión: De nuestros resultados parece deducirse que aquellos niños que presentan una ITU por gérmenes no E. coli presentan más frecuentemente malformaciones nefrourológicas (AU)


Introduction: It is pointed out that non E. coli urinary tract infections (UTI) are more frequently related to vesicoureteral anomalies and renal scarring. This research aims to analyse the laboratory features and imaging studies (urinary tract ultrasound and cycystourethrography) in hospitalized infants diagnosed as first UTI, as well as evaluating possible differences between those caused by E. coli or other pathogens. Patients and methods: Between 2003 and 2007, medical databases of 203 infants hospitalized in our department for first UTI were reviewed. Initial laboratory data and imaging studies (urinary tract ultrasound and cystourethrography) were collected, together with the follow-up of every infant in outpatient services. Results: Out of the 203 infants included in the research study, 174 (85,7%) were diagnosed as E. coli UTI and 29 (14,3%) as UTI caused by other pathogens. More urinary tract ultrasound anomalies were noted in the latter compared to non E. coli: O.R. = 2.31 (1,12-6,05). In this way they showed higher rates of urinary tract anomalies, if we consider these ones as anomalies in ultrasound and/or cystourethrography, with OR=4.57 (2,01-10,4). We also detected that infants with non E. coli UTI yielded a higher association with ≥3 vesicoureteral reflux compared to E coli UTI: OR = 7,9 (2,68-27,2) P<0,05. We have not detected any other differences between E. coli and non E. Coli UTIs (epidemiologic and laboratory data). Conclusion: According to these results, we assume that infants who suffer form a non- E. coli first UTI are more commonly linked to urinary tract anomalies (AU)


Subject(s)
Humans , Male , Female , Child , Urinary Tract Infections/complications , Escherichia coli/pathogenicity , Urinary Tract Infections/etiology , Vesico-Ureteral Reflux/etiology , Retrospective Studies
7.
An Pediatr (Barc) ; 68(5): 462-5, 2008 May.
Article in Spanish | MEDLINE | ID: mdl-18447990

ABSTRACT

OBJECTIVE: The advantages of breastfeeding for child and mother are widely recognised. Many factors seem to influence the mother's decision of breastfeed. The immigrant state of parents is one of the relevant factors considered. Previous studies founded higher breastfeeding rates among the immigrant population. The present work studies the rates of starting and duration of breastfeeding in the Spanish native population and in immigrants, as well as its relationship with other factors, such as tobacco habit and other perinatal factors. METHODS: The study included 911 children over a 10 months period. Age, sex, pregnancy duration, birth weight, parents' age, parent's smoking habits and smoking during pregnancy and their relationship the starting and duration of breastfeeding (OR and 95 % CI was obtained) in both immigrant and native population groups and a final multivariate analysis was performed for the starting of breastfeeding and continuing it at three months, including all studied variables. RESULTS: Immigrant and Native population were similar in all variables apart from mother age and smoking habit. Only mother smoking status (initial: OR 0.610 [ 0.429-0.867]; three months: OR 0.540 [0.458-0.636]) and birth weight (initial: OR 0.411 [0.268-0.629]; three months: OR 0.525 [0.407-0.677]) reached statistical significance in the final multivariate analysis. CONCLUSION: Our findings show that smoking habit and low birth weight are risk factors for not breastfeeding. Immigration status seems to be a confounding factor.


Subject(s)
Breast Feeding/ethnology , Breast Feeding/statistics & numerical data , Emigration and Immigration/statistics & numerical data , Smoking/ethnology , Adult , Female , Humans , Infant , Infant, Newborn , Male , Prevalence , Smoking/epidemiology , Spain/epidemiology , Surveys and Questionnaires
8.
An. pediatr. (2003, Ed. impr.) ; 68(5): 462-465, mayo 2008. tab
Article in Es | IBECS | ID: ibc-64573

ABSTRACT

Objetivo: Los beneficios de la lactancia materna para los niños y las madres están generalmente reconocidos. Muchos factores influyen en el inicio de la lactancia materna. Entre ellos se ha señalado el estatus de inmigrantes de los padres. Algunos estudios han señalado elevadas tasas de lactancia materna entre la población inmigrante. El presente trabajo estudia la lactancia materna en población española e inmigrante, y su relación con otros factores del período neonatal. Métodos: Se han estudiado 911 niños durante un período de 10 meses, se recogieron datos sobre edad, sexo, duración del embarazo, peso al nacimiento, edad y hábito tabáquico de los padres durante el embarazo, y su relación con el inicio de lactancia materna y su duración (odds ratio [OR] e intervalo de confianza [IC] del 95 %) en los grupos de población inmigrante y autóctona, realizándose también análisis multivariante incluyendo todas las variables estudiadas. Resultados: Las variables estudiadas fueron similares entre la población autóctona y la inmigrante excepto la edad materna y el hábito tabáquico. En el análisis multivariante sólo presentaron significación estadística con la lactancia materna el hábito tabáquico de la madre (inicio: OR 0,610 [IC 95 %: 0,419-0,867]; a los 3 meses: OR 0,540 [IC 95 %: 0,458-0,636] y el peso al nacimiento < 2.500 g (inicio: OR 0,411 [IC 95 %: 0,268-0,629]; 3 meses: OR 0,525 [IC 95 %: 0,407-0,677]. Conclusión: Nuestros datos señalan que los factores de riesgo para el no inicio de la lactancia materna o su no mantenimiento a los 3 meses son el bajo peso al nacimiento y el tabaquismo materno. El ser inmigrante se ha comportado como un factor de confusión (AU)


Objective: The advantages of breastfeeding for child and mother are widely recognised. Many factors seem to influence the mother’s decision of breastfeed. The immigrant state of parents is one of the relevant factors considered. Previous studies founded higher breastfeeding rates among the immigrant population. The present work studies the rates of starting and duration of breastfeeding in the Spanish native population and in immigrants, as well as its relationship with other factors, such as tobacco habit and other perinatal factors. Methods: The study included 911 children over a 10 months period. Age, sex, pregnancy duration, birth weight, parents’ age, parent’s smoking habits and smoking during pregnancy and their relationship the starting and duration of breastfeeding (OR and 95 % CI was obtained) in both immigrant and native population groups and a final multivariate analysis was performed for the starting of breastfeeding and continuing it at three months, including all studied variables. Results: Immigrant and Native population were similar in all variables apart from mother age and smoking habit. Only mother smoking status (initial: OR 0.610 [ 0.429-0.867]; three months: OR 0.540 [0.458-0.636]) and birth weight (initial: OR 0.411 [0.268-0.629]; three months: OR 0.525 [0.407-0.677]) reached statistical significance in the final multivariate analysis. Conclusion: Our findings show that smoking habit and low birth weight are risk factors for not breastfeeding. Immigration status seems to be a confounding factor (AU)


Subject(s)
Humans , Male , Female , Adolescent , Students/psychology , Tobacco Use Disorder/epidemiology , Tobacco Use Disorder/psychology , Tobacco Smoke Pollution/prevention & control , Tobacco Use Disorder/epidemiology , Tobacco Use Disorder/prevention & control , Health Knowledge, Attitudes, Practice , Surveys and Questionnaires , Adaptation, Psychological/physiology , Adolescent Behavior/psychology , Education, Primary and Secondary , Prospective Studies , Longitudinal Studies , Logistic Models
9.
Rev. esp. pediatr. (Ed. impr.) ; 64(2): 126-129, mar.-abr. 2008. ilus, tab
Article in Spanish | IBECS | ID: ibc-60244

ABSTRACT

Antecedentes: Las gastroenteritis (GEA) nosocomiales son una complicación frecuente en las áreas de hospitalización pediátrica. Objetivo: Estudiar los posibles factores de riesgo para la presencia de gastroenteritis nosocomiales. Métodos: Estudio de los niños de hasta 24 meses de edad ingresados en la Sección de Lactantes de nuestro Hospital. Se analizaron separadamente los grupos con gastroenteritis adquirida en la comunidad, gastroenteritis nosocomial y no gastroenteritis. Resultados: De los 1.517 niños ingresados, 228 presentaron GEA y de ellos en 39 casos se trató de una GEA nosocomial. En 77 casos se detectó rotavirus y en 22, bacterias enteropatógenas. La incidencia acumulada de GEA nosocomial por 100 pacientes fue de 2,98% y la tasa o densidad de incidencia por 100 estancias fue de 0,51. No se encontraron diferencias significativas en cuanto a la edad entre los 3 grupos. La estancia media de los niños con GEA nosocomial fue significativamente mayor y se encontraron odds ratio de 4,87 (IC 1,94-12,2) para los niños con estancias entre 6 y 10 días y 15,93 (IC 5,89-43) para aquellos con estancias mayores de 10 días respecto a los que tuvieron estancias menores de 6 días. Conclusiones: La probabilidad de presentar una GEA nosocomial se incrementa con la prolongación de la estancia hospitalaria. Disminuir los días de estancia debe ser un objetivo par aprevenir las GEA nosocomiales (AU)


Precedents: The osocomial gastroenteritis (GEA) is a frequent complication in the areas of paediatric hospitalization. Aim: To study the relation between the days that remain entered the patients and the nosocomial gastroenteritis. Methods: Study of the children of up to 24 months of age joined the Section of Infants of our hospital. The groups were analyzed separately by gastroenteritis acquired in the community, nosocomial gastroenteritis and not gastroenteritis. Results: Of 1.517 entered children, 228 presented GEA and of them in 39 cases treat of a nosocomial GEA. In 77 cases detect rotavirus and in 22 enteropatogenic bacteria. The incident accumulated of nosocomial GEA by 100 patients was of 0,51. They did not find significant differences as for the age in 3 groups. The average stay of the children with nosocomial GEA was significantly major and they found odds ratio of 4,87 (IC 1,94-12,2) for the children between 6 and 10 days and 15,93 (IC 5,98-43) for those with major stays of 10 days with regard to those who had minor stays of 6 days. Conclusions: The probability of presenting a nosocomial GEA increases with the prolongation of the hospitable stay. To diminish the days of stay must be an aim to prevent the nosocomial GEAs (AU)


Subject(s)
Humans , Male , Female , Infant , Gastroenteritis/epidemiology , Cross Infection/epidemiology , Rotavirus Infections/epidemiology , /statistics & numerical data , Rotavirus/isolation & purification , Diarrhea, Infantile/epidemiology
10.
Prev. tab ; 9(3): 113-116, jul.-sept. 2007. tab
Article in Spanish | IBECS | ID: ibc-78937

ABSTRACT

Objetivo: Conocer el porcentaje de mujeres que dejan de fumar durante el embarazo y las que recaen en el habito seis meses después del parto. Método: Encuesta a madres con niños hospitalizados con 6 o más meses de edad de enero de 2000 a octubre de 2006. Resultados: Un 57,55% de las fumadoras abandonaron el hábito durante el embarazo. A los seis meses el 36,01% había vuelto a fumar. La edad de las que continuaron sin fumar era significativamente mayor que la de las que no dejaron de fumar, y la de las que habiéndolo dejado, a los seis meses habían vuelto a fumar. No se encontraron diferencias significativas en los años analizados en las tasas de abandono del hábito tabáquico ni en el de recaídas. El porcentaje de padres no fumadores y de lactancia materna fue significativamente mayor en el caso de las madres que no volvieron a reiniciar el hábito en relación a lasque no dejaron de fumar y las que recayeron. Conclusiones: El número de mujeres que continúan fumando durante el embarazo es elevado, aunque un número importante deja el hábito en este momento. El porcentaje de recaídas en las que abandona el hábito también es preocupante. Es aconsejable una política más activa, tanto para aumentar el número de abandonos del tabaquismo durante el embarazo como para prevenir las recaídas (AU)


Objective: Know the percentage of women who quit smoking during pregnancy and those who relapse in the habit 6 months after giving birth. Method: Survey of mothers with hospitalized children who are 6 months or older from January 2000 to October 2006. Results: A total of 57.55% of the smokers quit the habit during pregnancy. At 6 months, 36.01% had begun to smoke again. Age of those who continued without smoking was significantly greater than those who did not quit and that of those who having quit, had begun to smoke again at 6 months. There were no significant differences in the years analyzed in the smoking habit abandonment rates or in the relapses. The percentages of non-smoking parents and maternal lactancy was significantly greater in the case of the mothers who did not reinitiate smoking in relationship to those who did not quit and those who relapsed. Conclusions: The number of women who continue to smoke during pregnancy is elevated, although a significant number quit at that time. The percentage of relapses in those who had quit is also of concern. A more active policy should be taken both to increase the number of those who quit smoking during pregnancy as well as to prevent the relapses (AU)


Subject(s)
Humans , Female , Pregnancy , Adult , Smoking/epidemiology , Smoking Prevention , Tobacco Smoke Pollution/prevention & control , Pregnancy Complications/epidemiology , Smoking Cessation/psychology , Tobacco Use Cessation/methods , Data Collection/methods , Socioeconomic Survey
11.
Rev. esp. pediatr. (Ed. impr.) ; 61(2): 110-113, mar.-abr. 2005.
Article in Spanish | IBECS | ID: ibc-121900

ABSTRACT

Objetivo. Conocer la incidencia de leishmaniasis visceral infantil en nuestro Hospital en los últimos 10 años y compararlo con estudios previos publicados. Material y métodos. Se realiza un estudio descriptivo retrospectivo de los casos de leishmaniasis infantil entre 1993 y junio 2004 en nuestro Hospital. Se obtienen 18 casos de los que recogemos los siguientes datos: edad, sexo, domicilio, antecedentes personales, clínica, exploración, pruebas complementarias, diagnóstico, tratamiento y seguimiento. Resultados. La incidencia de la enfermedad fue de 2-3 casos al año, con un pico máximo en el 2002; la mayoría procedían de Madrid, encontrándose sólo en dos casos antecedentes de interés. En la serie obtenida 11 fueron varones y 7 mujeres, con un rango de edad entre los 4 meses y los 9 años. La fiebre se presentó en todos los pacientes acompañándose de otros síntomas como astenia y anorexia; en la exploración física destacó la esplenomegalia, seguida de la palidez cutánea y hepatomegalia. En los parámetros sanguíneos todos presentaron anemia y en algunos casos otros datos como plaquetopenia, leucopenia, transaminasas e IgG elevadas. En todos los casos fue positivo el aspirado de médula ósea; de éstos un 78% tenía antícuerpos antileishmania positivos. El tratamiento de elección en 17 casos fue antimoniato de meglumina y un caso anfotericina B. Conclusiones. La leishmaniasis continúa siendo un problema en nuestro medio, afectando a niños con edades comprendidas entre 1 y 3 años por la vulnerabilidad de sus sistema inmune y sin tener una historia de contagio aparente (AU)


Objective. Knowing the incidence of the visceral leishmaniasis in children within our hospital in the last 10 years and comparing it with previous papers. Children and methods. A retrospective study of cases with leishmaniasis between 1993 and June of 2004 in our hospital has been carried out. 18 cases have been obtained, the following features have been collected for them: age, sex, address, personal records, symptoms, physical examination, laboratory testing, diagnosis, treatment and monitoring. Results. The disease incidence was 2-3 cases annually, with the maximum value in 2002; most of them were form Madrid, and only two cases presented animal contact. They were 11 boys and 7 girls, with a range of ages between 4 months and 9 years. Every patient had fever and some of them presented other symptoms such as asthenia and anorexia. The splenomegaly was the principal sign, followed by the pale skin and hepatomegaly. All of them presented anemia and some of them showed low blood platelets, leucopenia and high value of transaminasas and IgG. In every case the parasite could be seen in the bone marrow. 78% of them had positive antileishmania antibodies. The principal drug used within the treatment was the Antimoniato de Meglumina and in just one case Anfotericine B. Conclusions. The leishmaniasis is still a problem in our environment, affecting 1 to 3 years old children because of their immature immunodeficiency (AU)


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Leishmaniasis, Visceral/epidemiology , Leishmania/pathogenicity , Meglumine/therapeutic use , Retrospective Studies , Age and Sex Distribution , Amphotericin B/therapeutic use , Bone Marrow Cells/pathology
12.
An Esp Pediatr ; 39(4): 317-9, 1993 Oct.
Article in Spanish | MEDLINE | ID: mdl-8256952

ABSTRACT

Some of the causes which may account for the high incidence of tuberculosis in children in our environment have been analyzed. Twelve cases of tuberculosis have been included in the study (seven pulmonary cases, two cases of bone tuberculosis, one nodosum erythema and one miliary tuberculosis in an HIV positive patient). Based upon our series, we report on some mistakes in the diagnosis, specific treatment and chemoprophylaxis. We have tried to briefly outline the steps which should be taken to overcome these problems.


Subject(s)
Tuberculosis, Pulmonary/diagnosis , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Antitubercular Agents/therapeutic use , Child, Preschool , Erythema Nodosum/diagnosis , Erythema Nodosum/drug therapy , Female , Humans , Infant , Male , Tuberculosis, Miliary/diagnosis , Tuberculosis, Miliary/drug therapy , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis, Osteoarticular/drug therapy , Tuberculosis, Pulmonary/drug therapy
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