Subject(s)
Humans , Male , Young Adult , Accidents, Traffic , Diaphragm/diagnostic imaging , Diaphragm/injuries , Rupture , Tomography, X-Ray ComputedABSTRACT
Donation after circulatory death (DCD) or controlled cardiac death (Maastricht type III donors) is that in which the irreversible cessation of circulatory and respiratory function occurs after the withdrawal of life-sustaining therapies. The shortage of available donor lungs has prompted the development of programs of controlled DCD for lung transplantation. The combined thorax-abdomen extraction in these cases is carried out only in a few centers in Spain, being even more exceptional considering the combined use of super rapid lung extraction with abdominal normothermic regional perfusion. The success achieved with the first cases of combined thorax-abdomen extraction in Maastricht type III donors in Navarra shows that it is a feasible and safe procedure.
Subject(s)
Lung Transplantation/methods , Tissue Donors/supply & distribution , Tissue and Organ Harvesting/methods , Death , Humans , Perfusion/methods , SpainSubject(s)
Antimetabolites, Antineoplastic/adverse effects , Antiviral Agents/adverse effects , Bromodeoxyuridine/analogs & derivatives , Fluorouracil/adverse effects , Aged , Antimetabolites, Antineoplastic/administration & dosage , Antiviral Agents/administration & dosage , Bromodeoxyuridine/administration & dosage , Bromodeoxyuridine/adverse effects , Diagnostic Errors , Drug Interactions , Fatal Outcome , Fluorouracil/administration & dosage , Herpes Zoster/diagnosis , Herpes Zoster/drug therapy , Humans , MaleABSTRACT
Donation after circulatory death (Maastricht type III donation) or controlled cardiac death refers to the retrieval of organs for transplantation purposes following death confirmed using circulatory criteria after the withdrawal of life support. The persistent shortfall in organ availability has prompted the development of donation programs following circulatory death for lung transplantation. The combined thorax-abdomen extraction in these cases is carried out in only twelve centres in Spain, while the combined use of abdominal normothermic regional perfusion (NRP) is even more exceptional. The first case of pulmonary and abdominal extraction in a Maastricht type III donor in Navarre with this type of preservation techniques is a milestone and the success achieved shows that it is a feasible and safe procedure.
